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Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models.
J Exp Clin Cancer Res. 2018 Jul 9;37(1):140. doi: 10.1186/s13046-018-0820-5.
J Exp Clin Cancer Res. 2018.
PMID: 29986755
Free PMC article.
Lack of growth inhibitory synergism with combined MAPK/PI3K inhibition in preclinical models of pancreatic cancer.
Ciuffreda L, Del Curatolo A, Falcone I, Conciatori F, Bazzichetto C, Cognetti F, Corbo V, Scarpa A, Milella M.
Ciuffreda L, et al. Among authors: del curatolo a.
Ann Oncol. 2017 Nov 1;28(11):2896-2898. doi: 10.1093/annonc/mdx335.
Ann Oncol. 2017.
PMID: 28666315
Free article.
No abstract available.
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PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.
Milella M, Falcone I, Conciatori F, Matteoni S, Sacconi A, De Luca T, Bazzichetto C, Corbo V, Simbolo M, Sperduti I, Benfante A, Del Curatolo A, Cesta Incani U, Malusa F, Eramo A, Sette G, Scarpa A, Konopleva M, Andreeff M, McCubrey JA, Blandino G, Todaro M, Stassi G, De Maria R, Cognetti F, Del Bufalo D, Ciuffreda L.
Milella M, et al. Among authors: del curatolo a.
Sci Rep. 2017 Feb 21;7:43013. doi: 10.1038/srep43013.
Sci Rep. 2017.
PMID: 28220839
Free PMC article.
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Advances towards the design and development of personalized non-small-cell lung cancer drug therapy.
Vari S, Pilotto S, Maugeri-Saccà M, Ciuffreda L, Cesta Incani U, Falcone I, Del Curatolo A, Ceribelli A, Gelibter A, De Maria R, Tortora G, Cognetti F, Bria E, Milella M.
Vari S, et al. Among authors: del curatolo a.
Expert Opin Drug Discov. 2013 Nov;8(11):1381-97. doi: 10.1517/17460441.2013.843523. Epub 2013 Oct 3.
Expert Opin Drug Discov. 2013.
PMID: 24088065
Review.
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PTEN expression and function in adult cancer stem cells and prospects for therapeutic targeting.
Ciuffreda L, Falcone I, Incani UC, Del Curatolo A, Conciatori F, Matteoni S, Vari S, Vaccaro V, Cognetti F, Milella M.
Ciuffreda L, et al. Among authors: del curatolo a.
Adv Biol Regul. 2014 Sep;56:66-80. doi: 10.1016/j.jbior.2014.07.002. Epub 2014 Jul 19.
Adv Biol Regul. 2014.
PMID: 25088603
Review.
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PTEN: Multiple Functions in Human Malignant Tumors.
Milella M, Falcone I, Conciatori F, Cesta Incani U, Del Curatolo A, Inzerilli N, Nuzzo CM, Vaccaro V, Vari S, Cognetti F, Ciuffreda L.
Milella M, et al. Among authors: del curatolo a.
Front Oncol. 2015 Feb 16;5:24. doi: 10.3389/fonc.2015.00024. eCollection 2015.
Front Oncol. 2015.
PMID: 25763354
Free PMC article.
Review.
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Loss of FGFR4 promotes the malignant phenotype of PDAC.
D'Agosto S, Pezzini F, Veghini L, Delfino P, Fiorini C, Temgue Tane GD, Del Curatolo A, Vicentini C, Ferrari G, Pasini D, Andreani S, Lupo F, Fiorini E, Lorenzon G, Lawlor RT, Rusev B, Malinova A, Luchini C, Milella M, Sereni E, Pea A, Bassi C, Bailey P, Scarpa A, Bria E, Corbo V.
D'Agosto S, et al. Among authors: del curatolo a.
Oncogene. 2022 Sep;41(38):4371-4384. doi: 10.1038/s41388-022-02432-5. Epub 2022 Aug 13.
Oncogene. 2022.
PMID: 35963908
Free PMC article.
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