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High-resolution 3D imaging of fixed and cleared organoids.
Dekkers JF, Alieva M, Wellens LM, Ariese HCR, Jamieson PR, Vonk AM, Amatngalim GD, Hu H, Oost KC, Snippert HJG, Beekman JM, Wehrens EJ, Visvader JE, Clevers H, Rios AC. Dekkers JF, et al. Nat Protoc. 2019 Jun;14(6):1756-1771. doi: 10.1038/s41596-019-0160-8. Epub 2019 May 3. Nat Protoc. 2019. PMID: 31053799
PPARγ as a therapeutic target in cystic fibrosis.
Dekkers JF, van der Ent CK, Kalkhoven E, Beekman JM. Dekkers JF, et al. Trends Mol Med. 2012 May;18(5):283-91. doi: 10.1016/j.molmed.2012.03.004. Epub 2012 Apr 9. Trends Mol Med. 2012. PMID: 22494945 Review.
CFTR-mutation specific applications of CFTR-directed monoclonal antibodies.
van Meegen MA, Terheggen SW, Koymans KJ, Vijftigschild LA, Dekkers JF, van der Ent CK, Beekman JM. van Meegen MA, et al. Among authors: dekkers jf. J Cyst Fibros. 2013 Sep;12(5):487-96. doi: 10.1016/j.jcf.2012.12.005. Epub 2013 Jan 11. J Cyst Fibros. 2013. PMID: 23317763 Free article.
A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. Dekkers JF, et al. Nat Med. 2013 Jul;19(7):939-45. doi: 10.1038/nm.3201. Epub 2013 Jun 2. Nat Med. 2013. PMID: 23727931
Modulation of the maladaptive stress response to manage diseases of protein folding.
Roth DM, Hutt DM, Tong J, Bouchecareilh M, Wang N, Seeley T, Dekkers JF, Beekman JM, Garza D, Drew L, Masliah E, Morimoto RI, Balch WE. Roth DM, et al. Among authors: dekkers jf. PLoS Biol. 2014 Nov 18;12(11):e1001998. doi: 10.1371/journal.pbio.1001998. eCollection 2014 Nov. PLoS Biol. 2014. PMID: 25406061 Free PMC article.
Modeling rotavirus infection and antiviral therapy using primary intestinal organoids.
Yin Y, Bijvelds M, Dang W, Xu L, van der Eijk AA, Knipping K, Tuysuz N, Dekkers JF, Wang Y, de Jonge J, Sprengers D, van der Laan LJ, Beekman JM, Ten Berge D, Metselaar HJ, de Jonge H, Koopmans MP, Peppelenbosch MP, Pan Q. Yin Y, et al. Among authors: dekkers jf. Antiviral Res. 2015 Nov;123:120-31. doi: 10.1016/j.antiviral.2015.09.010. Epub 2015 Sep 25. Antiviral Res. 2015. PMID: 26408355
rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.
Vidović D, Carlon MS, da Cunha MF, Dekkers JF, Hollenhorst MI, Bijvelds MJ, Ramalho AS, Van den Haute C, Ferrante M, Baekelandt V, Janssens HM, De Boeck K, Sermet-Gaudelus I, de Jonge HR, Gijsbers R, Beekman JM, Edelman A, Debyser Z. Vidović D, et al. Among authors: dekkers jf. Am J Respir Crit Care Med. 2016 Feb 1;193(3):288-98. doi: 10.1164/rccm.201505-0914OC. Am J Respir Crit Care Med. 2016. PMID: 26509335
37 results