Dekker H - Search Results

1

Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function.

Van Der Steen N, Keller K, Dekker H, Porcelli L, Honeywell RJ, Van Meerloo J, Musters RJP, Kathmann I, Frampton AE, Liu DSK, Ruijtenbeek R, Rolfo C, Pauwels P, Giovannetti E, Peters GJ. Van Der Steen N, et al. Among authors: dekker h. J Cell Physiol. 2020 Nov;235(11):8085-8097. doi: 10.1002/jcp.29463. Epub 2020 Jan 20. J Cell Physiol. 2020. PMID: 31960422 Free PMC article.

2

Measurement of in vitro cellular pharmacokinetics of 5-fluorouracil in human and rat cancer cell lines and rat hepatocytes using a flow-through system.

Spoelstra EC, Pinedo HM, Dekker H, Peters GJ, Lankelma J. Spoelstra EC, et al. Among authors: dekker h. Cancer Chemother Pharmacol. 1991;27(4):320-5. doi: 10.1007/BF00685119. Cancer Chemother Pharmacol. 1991. PMID: 1998989

3

Folate deprivation induces BCRP (ABCG2) expression and mitoxantrone resistance in Caco-2 cells.

Lemos C, Kathmann I, Giovannetti E, Dekker H, Scheffer GL, Calhau C, Jansen G, Peters GJ. Lemos C, et al. Among authors: dekker h. Int J Cancer. 2008 Oct 1;123(7):1712-20. doi: 10.1002/ijc.23677. Int J Cancer. 2008. PMID: 18623116 Free article.

4

Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.

Gotink KJ, Broxterman HJ, Labots M, de Haas RR, Dekker H, Honeywell RJ, Rudek MA, Beerepoot LV, Musters RJ, Jansen G, Griffioen AW, Assaraf YG, Pili R, Peters GJ, Verheul HM. Gotink KJ, et al. Among authors: dekker h. Clin Cancer Res. 2011 Dec 1;17(23):7337-46. doi: 10.1158/1078-0432.CCR-11-1667. Epub 2011 Oct 6. Clin Cancer Res. 2011. PMID: 21980135 Free PMC article.

5

Kinome profiling of non-canonical TRAIL signaling reveals RIP1-Src-STAT3-dependent invasion in resistant non-small cell lung cancer cells.

Azijli K, Yuvaraj S, Peppelenbosch MP, Würdinger T, Dekker H, Joore J, van Dijk E, Quax WJ, Peters GJ, de Jong S, Kruyt FA. Azijli K, et al. Among authors: dekker h. J Cell Sci. 2012 Oct 1;125(Pt 19):4651-61. doi: 10.1242/jcs.109587. Epub 2012 Jul 13. J Cell Sci. 2012. PMID: 22797920

6

Molecular mechanisms and modulation of key pathways underlying the synergistic interaction of sorafenib with erlotinib in non-small-cell-lung cancer (NSCLC) cells.

Giovannetti E, Labots M, Dekker H, Galvani E, Lind JS, Sciarrillo R, Honeywell R, Smit EF, Verheul HM, Peters GJ. Giovannetti E, et al. Among authors: dekker h. Curr Pharm Des. 2013;19(5):927-39. Curr Pharm Des. 2013. PMID: 22973961

7

Molecular mechanisms underlying the antitumor activity of 3-aminopropanamide irreversible inhibitors of the epidermal growth factor receptor in non-small cell lung cancer.

Galvani E, Giovannetti E, Saccani F, Cavazzoni A, Leon LG, Dekker H, Alfieri R, Carmi C, Mor M, Ardizzoni A, Petronini PG, Peters GJ. Galvani E, et al. Among authors: dekker h. Neoplasia. 2013 Jan;15(1):61-72. doi: 10.1593/neo.121434. Neoplasia. 2013. PMID: 23359111 Free PMC article.

8

Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature.

Gotink KJ, Broxterman HJ, Honeywell RJ, Dekker H, de Haas RR, Miles KM, Adelaiye R, Griffioen AW, Peters GJ, Pili R, Verheul HM. Gotink KJ, et al. Among authors: dekker h. Oncoscience. 2014 Dec 15;1(12):844-53. doi: 10.18632/oncoscience.106. eCollection 2014. Oncoscience. 2014. PMID: 25621299 Free PMC article.

9

Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters.

Da Silva CG, Honeywell RJ, Dekker H, Peters GJ. Da Silva CG, et al. Among authors: dekker h. Expert Opin Drug Metab Toxicol. 2015 May;11(5):703-17. doi: 10.1517/17425255.2015.1006626. Epub 2015 Jan 29. Expert Opin Drug Metab Toxicol. 2015. PMID: 25633410 Review.

10

Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib.

Gotink KJ, Rovithi M, de Haas RR, Honeywell RJ, Dekker H, Poel D, Azijli K, Peters GJ, Broxterman HJ, Verheul HM. Gotink KJ, et al. Among authors: dekker h. Cell Oncol (Dordr). 2015 Apr;38(2):119-29. doi: 10.1007/s13402-015-0218-8. Epub 2015 Feb 11. Cell Oncol (Dordr). 2015. PMID: 25665527 Free PMC article.

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