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Preclinical Evaluation of 225Ac-Labeled Single-Domain Antibody for the Treatment of HER2pos Cancer.
Mol Cancer Ther. 2022 Dec 2;21(12):1835-1845. doi: 10.1158/1535-7163.MCT-21-1021.
Mol Cancer Ther. 2022.
PMID: 36129807
Free PMC article.
Targeted alpha therapy using short-lived alpha-particles and the promise of nanobodies as targeting vehicle.
Dekempeneer Y, Keyaerts M, Krasniqi A, Puttemans J, Muyldermans S, Lahoutte T, D'huyvetter M, Devoogdt N.
Dekempeneer Y, et al.
Expert Opin Biol Ther. 2016 Aug;16(8):1035-47. doi: 10.1080/14712598.2016.1185412. Epub 2016 May 19.
Expert Opin Biol Ther. 2016.
PMID: 27145158
Free PMC article.
Review.
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Labeling of Anti-HER2 Nanobodies with Astatine-211: Optimization and the Effect of Different Coupling Reagents on Their in Vivo Behavior.
Dekempeneer Y, Bäck T, Aneheim E, Jensen H, Puttemans J, Xavier C, Keyaerts M, Palm S, Albertsson P, Lahoutte T, Caveliers V, Lindegren S, D'Huyvetter M.
Dekempeneer Y, et al.
Mol Pharm. 2019 Aug 5;16(8):3524-3533. doi: 10.1021/acs.molpharmaceut.9b00354. Epub 2019 Jul 3.
Mol Pharm. 2019.
PMID: 31268724
Free article.
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Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies.
Puttemans J, Dekempeneer Y, Eersels JL, Hanssens H, Debie P, Keyaerts M, Windhorst AD, van der Aa F, Lecocq Q, Breckpot K, Morgenstern A, Bruchertseifer F, Lahoutte T, Devoogdt N, D'Huyvetter M.
Puttemans J, et al. Among authors: dekempeneer y.
Cancers (Basel). 2020 Apr 21;12(4):1017. doi: 10.3390/cancers12041017.
Cancers (Basel). 2020.
PMID: 32326199
Free PMC article.
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Therapeutic Efficacy of 213Bi-labeled sdAbs in a Preclinical Model of Ovarian Cancer.
Dekempeneer Y, Caveliers V, Ooms M, Maertens D, Gysemans M, Lahoutte T, Xavier C, Lecocq Q, Maes K, Covens P, Miller BW, Bruchertseifer F, Morgenstern A, Cardinaels T, D'Huyvetter M.
Dekempeneer Y, et al.
Mol Pharm. 2020 Sep 8;17(9):3553-3566. doi: 10.1021/acs.molpharmaceut.0c00580. Epub 2020 Aug 13.
Mol Pharm. 2020.
PMID: 32787284
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Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment.
Ertveldt T, Krasniqi A, Ceuppens H, Puttemans J, Dekempeneer Y, Jonghe K, Mey W, Lecocq Q, Vlaeminck Y, Awad RM, Goyvaerts C, Veirman K, Morgenstern A, Bruchertseifer F, Keyaerts M, Devoogdt N, D'Huyvetter M, Breckpot K.
Ertveldt T, et al. Among authors: dekempeneer y.
J Nucl Med. 2023 May;64(5):751-758. doi: 10.2967/jnumed.122.264752. Epub 2023 Apr 13.
J Nucl Med. 2023.
PMID: 37055223
Free article.
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Preclinical Evaluation of a Radiotheranostic Single-Domain Antibody Against Fibroblast Activation Protein α.
Dekempeneer Y, Massa S, Santens F, Navarro L, Berdal M, Lucero MM, Pombo Antunes AR, Lahoutte T, Van Ginderachter JA, Devoogdt N, D'Huyvetter M.
Dekempeneer Y, et al.
J Nucl Med. 2023 Dec;64(12):1941-1948. doi: 10.2967/jnumed.123.266381.
J Nucl Med. 2023.
PMID: 38040444
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