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The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation.
Deuis JR, Ragnarsson L, Robinson SD, Dekan Z, Chan L, Jin AH, Tran P, McMahon KL, Li S, Wood JN, Cox JJ, King GF, Herzig V, Vetter I. Deuis JR, et al. Among authors: dekan z. Front Pharmacol. 2022 Jan 14;12:789570. doi: 10.3389/fphar.2021.789570. eCollection 2021. Front Pharmacol. 2022. PMID: 35095499 Free PMC article.
Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.
Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, Christie MJ, King GF, Alewood PF, Lewis RJ, Wood JN, Vetter I. Deuis JR, et al. Among authors: dekan z. Sci Rep. 2017 Jan 20;7:40883. doi: 10.1038/srep40883. Sci Rep. 2017. PMID: 28106092 Free PMC article.
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, King GF, Vetter I, Rash LD, Adams DJ, Alewood PF. Finol-Urdaneta RK, et al. Among authors: dekan z. Proc Natl Acad Sci U S A. 2022 Feb 1;119(5):e2110932119. doi: 10.1073/pnas.2110932119. Proc Natl Acad Sci U S A. 2022. PMID: 35074873 Free PMC article.
Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.
Mueller A, Dekan Z, Kaas Q, Agwa AJ, Starobova H, Alewood PF, Schroeder CI, Mobli M, Deuis JR, Vetter I. Mueller A, et al. Among authors: dekan z. ACS Pharmacol Transl Sci. 2020 Feb 19;3(3):535-546. doi: 10.1021/acsptsci.0c00002. eCollection 2020 Jun 12. ACS Pharmacol Transl Sci. 2020. PMID: 32566918 Free PMC article.
35 results