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A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites.
Milenkovic D, Berghe WV, Morand C, Claude S, van de Sandt A, Gorressen S, Monfoulet LE, Chirumamilla CS, Declerck K, Szic KSV, Lahtela-Kakkonen M, Gerhauser C, Merx MW, Kelm M. Milenkovic D, et al. Among authors: declerck k. Sci Rep. 2018 Oct 19;8(1):15487. doi: 10.1038/s41598-018-33959-x. Sci Rep. 2018. PMID: 30341379 Free PMC article.
Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease.
Istas G, Declerck K, Pudenz M, Szic KSV, Lendinez-Tortajada V, Leon-Latre M, Heyninck K, Haegeman G, Casasnovas JA, Tellez-Plaza M, Gerhauser C, Heiss C, Rodriguez-Mateos A, Berghe WV. Istas G, et al. Among authors: declerck k. Sci Rep. 2017 Jul 11;7(1):5120. doi: 10.1038/s41598-017-03434-0. Sci Rep. 2017. PMID: 28698603 Free PMC article.
(-)-Epicatechin metabolites promote vascular health through epigenetic reprogramming of endothelial-immune cell signaling and reversing systemic low-grade inflammation.
Milenkovic D, Declerck K, Guttman Y, Kerem Z, Claude S, Weseler AR, Bast A, Schroeter H, Morand C, Vanden Berghe W. Milenkovic D, et al. Among authors: declerck k. Biochem Pharmacol. 2020 Mar;173:113699. doi: 10.1016/j.bcp.2019.113699. Epub 2019 Nov 20. Biochem Pharmacol. 2020. PMID: 31756325
Flavanol Consumption in Healthy Men Preserves Integrity of Immunological-Endothelial Barrier Cell Functions: Nutri(epi)genomic Analysis.
Milenkovic D, Rodriguez-Mateos A, Lucosz M, Istas G, Declerck K, Sansone R, Deenen R, Köhrer K, Corral-Jara KF, Altschmied J, Haendeler J, Kelm M, Berghe WV, Heiss C. Milenkovic D, et al. Among authors: declerck k. Mol Nutr Food Res. 2022 Nov;66(21):e2100991. doi: 10.1002/mnfr.202100991. Epub 2022 Feb 16. Mol Nutr Food Res. 2022. PMID: 35094491 Free PMC article.
Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease.
Ruskovska T, Massaro M, Carluccio MA, Arola-Arnal A, Muguerza B, Vanden Berghe W, Declerck K, Bravo FI, Calabriso N, Combet E, Gibney ER, Gomes A, Gonthier MP, Kistanova E, Krga I, Mena P, Morand C, Nunes Dos Santos C, de Pascual-Teresa S, Rodriguez-Mateos A, Scoditti E, Suárez M, Milenkovic D. Ruskovska T, et al. Among authors: declerck k. Food Funct. 2020 Jun 24;11(6):5040-5064. doi: 10.1039/d0fo00701c. Food Funct. 2020. PMID: 32537624
Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state.
Milenkovic D, Vanden Berghe W, Boby C, Leroux C, Declerck K, Szarc vel Szic K, Heyninck K, Laukens K, Bizet M, Defrance M, Dedeurwaerder S, Calonne E, Fuks F, Haegeman G, Haenen GR, Bast A, Weseler AR. Milenkovic D, et al. Among authors: declerck k. PLoS One. 2014 Apr 24;9(4):e95527. doi: 10.1371/journal.pone.0095527. eCollection 2014. PLoS One. 2014. PMID: 24763279 Free PMC article.
Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells.
Logie E, Chirumamilla CS, Perez-Novo C, Shaw P, Declerck K, Palagani A, Rangarajan S, Cuypers B, De Neuter N, Mobashar Hussain Urf Turabe F, Kumar Verma N, Bogaerts A, Laukens K, Offner F, Van Vlierberghe P, Van Ostade X, Berghe WV. Logie E, et al. Among authors: declerck k. Cancers (Basel). 2021 Mar 31;13(7):1618. doi: 10.3390/cancers13071618. Cancers (Basel). 2021. PMID: 33807411 Free PMC article.
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.
Hassannia B, Wiernicki B, Ingold I, Qu F, Van Herck S, Tyurina YY, Bayır H, Abhari BA, Angeli JPF, Choi SM, Meul E, Heyninck K, Declerck K, Chirumamilla CS, Lahtela-Kakkonen M, Van Camp G, Krysko DV, Ekert PG, Fulda S, De Geest BG, Conrad M, Kagan VE, Vanden Berghe W, Vandenabeele P, Vanden Berghe T. Hassannia B, et al. Among authors: declerck k. J Clin Invest. 2018 Aug 1;128(8):3341-3355. doi: 10.1172/JCI99032. Epub 2018 Jun 25. J Clin Invest. 2018. PMID: 29939160 Free PMC article.
49 results