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Page 1
Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment.
Bosteels C, Van Damme KFA, De Leeuw E, Declercq J, Maes B, Bosteels V, Hoste L, Naesens L, Debeuf N, Deckers J, Cole B, Pardons M, Weiskopf D, Sette A, Weygaerde YV, Malfait T, Vandecasteele SJ, Demedts IK, Slabbynck H, Allard S, Depuydt P, Van Braeckel E, De Clercq J, Martens L, Dupont S, Seurinck R, Vandamme N, Haerynck F, Roychowdhury DF, Vandekerckhove L, Guilliams M, Tavernier SJ, Lambrecht BN. Bosteels C, et al. Among authors: debeuf n. Cell Rep Med. 2022 Dec 20;3(12):100833. doi: 10.1016/j.xcrm.2022.100833. Epub 2022 Nov 15. Cell Rep Med. 2022. PMID: 36459994 Free PMC article.
Mouse Models of Asthma.
Debeuf N, Haspeslagh E, van Helden M, Hammad H, Lambrecht BN. Debeuf N, et al. Curr Protoc Mouse Biol. 2016 Jun 1;6(2):169-184. doi: 10.1002/cpmo.4. Curr Protoc Mouse Biol. 2016. PMID: 27248433
Murine Models of Allergic Asthma.
Haspeslagh E, Debeuf N, Hammad H, Lambrecht BN. Haspeslagh E, et al. Among authors: debeuf n. Methods Mol Biol. 2017;1559:121-136. doi: 10.1007/978-1-4939-6786-5_10. Methods Mol Biol. 2017. PMID: 28063042
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice.
Debeuf N, Zhakupova A, Steiner R, Van Gassen S, Deswarte K, Fayazpour F, Van Moorleghem J, Vergote K, Pavie B, Lemeire K, Hammad H, Hornemann T, Janssens S, Lambrecht BN. Debeuf N, et al. J Allergy Clin Immunol. 2019 Dec;144(6):1648-1659.e9. doi: 10.1016/j.jaci.2019.06.041. Epub 2019 Jul 20. J Allergy Clin Immunol. 2019. PMID: 31330218 Free PMC article.
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Bosteels C, Neyt K, Vanheerswynghels M, van Helden MJ, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams DL, Tang SC, Mayer JU, Ronchese F, Scott CL, Hammad H, Guilliams M, Lambrecht BN. Bosteels C, et al. Among authors: debeuf n. Immunity. 2020 Jun 16;52(6):1039-1056.e9. doi: 10.1016/j.immuni.2020.04.005. Epub 2020 May 8. Immunity. 2020. PMID: 32392463 Free PMC article.
The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.
Maes B, Smole U, Vanderkerken M, Deswarte K, Van Moorleghem J, Vergote K, Vanheerswynghels M, De Wolf C, De Prijck S, Debeuf N, Pavie B, Toussaint W, Janssens S, Savvides S, Lambrecht BN, Hammad H. Maes B, et al. Among authors: debeuf n. J Allergy Clin Immunol. 2022 Apr;149(4):1413-1427.e2. doi: 10.1016/j.jaci.2021.08.020. Epub 2021 Sep 8. J Allergy Clin Immunol. 2022. PMID: 34506849
Emerging Paradigms in Type 2 Immunity.
Hammad H, Debeuf N, Aegerter H, Brown AS, Lambrecht BN. Hammad H, et al. Among authors: debeuf n. Annu Rev Immunol. 2022 Apr 26;40:443-467. doi: 10.1146/annurev-immunol-101320-030339. Annu Rev Immunol. 2022. PMID: 35471837 Review.
Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial.
De Leeuw E, Van Damme KFA, Declercq J, Bosteels C, Maes B, Tavernier SJ, Detalle L, Smart T, Glatt S, Debeuf N, Deckers J, Lameire S, Vandecasteele SJ, De Neve N, Demedts IK, Govaerts E, Knoop C, Vanhove K, Moutschen M, Terryn W, Depuydt P, Van Braeckel E, Haerynck F, Hendrickx TCJ, Parrein V, Lalla M, Brittain C, Lambrecht BN. De Leeuw E, et al. Among authors: debeuf n. Respir Res. 2022 Aug 9;23(1):202. doi: 10.1186/s12931-022-02126-2. Respir Res. 2022. PMID: 35945604 Free PMC article. Clinical Trial.
13 results