Debets R - Search Results

1

Vγ9Vδ2 T Cells Concurrently Kill Cancer Cells and Cross-Present Tumor Antigens.

Holmen Olofsson G, Idorn M, Carnaz Simões AM, Aehnlich P, Skadborg SK, Noessner E, Debets R, Moser B, Met Ö, Thor Straten P. Holmen Olofsson G, et al. Among authors: debets r. Front Immunol. 2021 Jun 2;12:645131. doi: 10.3389/fimmu.2021.645131. eCollection 2021. Front Immunol. 2021. PMID: 34149689 Free PMC article.

2

Genetic engineering of T cell specificity for immunotherapy of cancer.

Willemsen RA, Debets R, Chames P, Bolhuis RL. Willemsen RA, et al. Among authors: debets r. Hum Immunol. 2003 Jan;64(1):56-68. doi: 10.1016/s0198-8859(02)00730-9. Hum Immunol. 2003. PMID: 12507815 Review.

3

T cell retargeting with MHC class I-restricted antibodies: the CD28 costimulatory domain enhances antigen-specific cytotoxicity and cytokine production.

Willemsen RA, Ronteltap C, Chames P, Debets R, Bolhuis RL. Willemsen RA, et al. Among authors: debets r. J Immunol. 2005 Jun 15;174(12):7853-8. doi: 10.4049/jimmunol.174.12.7853. J Immunol. 2005. PMID: 15944290 Free article.

4

T cell re-targeting to EBV antigens following TCR gene transfer: CD28-containing receptors mediate enhanced antigen-specific IFNgamma production.

Schaft N, Lankiewicz B, Drexhage J, Berrevoets C, Moss DJ, Levitsky V, Bonneville M, Lee SP, McMichael AJ, Gratama JW, Bolhuis RL, Willemsen R, Debets R. Schaft N, et al. Among authors: debets r. Int Immunol. 2006 Apr;18(4):591-601. doi: 10.1093/intimm/dxh401. Epub 2006 Feb 28. Int Immunol. 2006. PMID: 16507598

5

Human TCR that incorporate CD3zeta induce highly preferred pairing between TCRalpha and beta chains following gene transfer.

Sebestyén Z, Schooten E, Sals T, Zaldivar I, San José E, Alarcón B, Bobisse S, Rosato A, Szöllosi J, Gratama JW, Willemsen RA, Debets R. Sebestyén Z, et al. Among authors: debets r. J Immunol. 2008 Jun 1;180(11):7736-46. doi: 10.4049/jimmunol.180.11.7736. J Immunol. 2008. PMID: 18490778

6

TCR gene-engineered T cell: limited T cell activation and combined use of IL-15 and IL-21 ensure minimal differentiation and maximal antigen-specificity.

Pouw N, Treffers-Westerlaken E, Mondino A, Lamers C, Debets R. Pouw N, et al. Among authors: debets r. Mol Immunol. 2010 Apr;47(7-8):1411-20. doi: 10.1016/j.molimm.2010.02.022. Mol Immunol. 2010. PMID: 20303179

7

TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets.

Straetemans T, van Brakel M, van Steenbergen S, Broertjes M, Drexhage J, Hegmans J, Lambrecht BN, Lamers C, van Der Bruggen P, Coulie PG, Debets R. Straetemans T, et al. Among authors: debets r. Clin Dev Immunol. 2012;2012:586314. doi: 10.1155/2012/586314. Epub 2012 Feb 12. Clin Dev Immunol. 2012. PMID: 22400038 Free PMC article.

8

An Altered gp100 Peptide Ligand with Decreased Binding by TCR and CD8α Dissects T Cell Cytotoxicity from Production of Cytokines and Activation of NFAT.

Schaft N, Coccoris M, Drexhage J, Knoop C, de Vries IJ, Adema GJ, Debets R. Schaft N, et al. Among authors: debets r. Front Immunol. 2013 Sep 4;4:270. doi: 10.3389/fimmu.2013.00270. eCollection 2013. Front Immunol. 2013. PMID: 24027572 Free PMC article.

9

TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu.

Kunert A, Straetemans T, Govers C, Lamers C, Mathijssen R, Sleijfer S, Debets R. Kunert A, et al. Among authors: debets r. Front Immunol. 2013 Nov 8;4:363. doi: 10.3389/fimmu.2013.00363. eCollection 2013. Front Immunol. 2013. PMID: 24265631 Free PMC article. Review.

10

TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.

Govers C, Sebestyén Z, Roszik J, van Brakel M, Berrevoets C, Szöőr Á, Panoutsopoulou K, Broertjes M, Van T, Vereb G, Szöllősi J, Debets R. Govers C, et al. Among authors: debets r. J Immunol. 2014 Nov 15;193(10):5315-26. doi: 10.4049/jimmunol.1302074. Epub 2014 Oct 15. J Immunol. 2014. PMID: 25320284

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