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Vaccination-based immunotherapy to target profibrotic cells in liver and lung.
Sobecki M, Chen J, Krzywinska E, Nagarajan S, Fan Z, Nelius E, Monné Rodriguez JM, Seehusen F, Hussein A, Moschini G, Hajam EY, Kiran R, Gotthardt D, Debbache J, Badoual C, Sato T, Isagawa T, Takeda N, Tanchot C, Tartour E, Weber A, Werner S, Loffing J, Sommer L, Sexl V, Münz C, Feghali-Bostwick C, Pachera E, Distler O, Snedeker J, Jamora C, Stockmann C. Sobecki M, et al. Among authors: debbache j. Cell Stem Cell. 2022 Oct 6;29(10):1459-1474.e9. doi: 10.1016/j.stem.2022.08.012. Epub 2022 Sep 15. Cell Stem Cell. 2022. PMID: 36113462 Free article.
Sox5 and chromatophores: switching pigment cell fates.
Debbache J, Sommer L. Debbache J, et al. Pigment Cell Melanoma Res. 2014 Nov;27(6):1004-5. doi: 10.1111/pcmr.12296. Epub 2014 Aug 12. Pigment Cell Melanoma Res. 2014. PMID: 25052154 No abstract available.
Injury-activated glial cells promote wound healing of the adult skin in mice.
Parfejevs V, Debbache J, Shakhova O, Schaefer SM, Glausch M, Wegner M, Suter U, Riekstina U, Werner S, Sommer L. Parfejevs V, et al. Among authors: debbache j. Nat Commun. 2018 Jan 16;9(1):236. doi: 10.1038/s41467-017-01488-2. Nat Commun. 2018. PMID: 29339718 Free PMC article.
EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
Zingg D, Debbache J, Peña-Hernández R, Antunes AT, Schaefer SM, Cheng PF, Zimmerli D, Haeusel J, Calçada RR, Tuncer E, Zhang Y, Bossart R, Wong KK, Basler K, Dummer R, Santoro R, Levesque MP, Sommer L. Zingg D, et al. Among authors: debbache j. Cancer Cell. 2018 Jul 9;34(1):69-84.e14. doi: 10.1016/j.ccell.2018.06.001. Epub 2018 Jun 28. Cancer Cell. 2018. PMID: 30008323 Free article.
The epigenetic modifier EZH2 controls melanoma growth and metastasis through silencing of distinct tumour suppressors.
Zingg D, Debbache J, Schaefer SM, Tuncer E, Frommel SC, Cheng P, Arenas-Ramirez N, Haeusel J, Zhang Y, Bonalli M, McCabe MT, Creasy CL, Levesque MP, Boyman O, Santoro R, Shakhova O, Dummer R, Sommer L. Zingg D, et al. Among authors: debbache j. Nat Commun. 2015 Jan 22;6:6051. doi: 10.1038/ncomms7051. Nat Commun. 2015. PMID: 25609585 Free article.
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma.
Shakhova O, Cheng P, Mishra PJ, Zingg D, Schaefer SM, Debbache J, Häusel J, Matter C, Guo T, Davis S, Meltzer P, Mihic-Probst D, Moch H, Wegner M, Merlino G, Levesque MP, Dummer R, Santoro R, Cinelli P, Sommer L. Shakhova O, et al. Among authors: debbache j. PLoS Genet. 2015 Jan 28;11(1):e1004877. doi: 10.1371/journal.pgen.1004877. eCollection 2015 Jan. PLoS Genet. 2015. PMID: 25629959 Free PMC article.
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