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Immune-epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children.
Magalhães VG, Lukassen S, Drechsler M, Loske J, Burkart SS, Wüst S, Jacobsen EM, Röhmel J, Mall MA, Debatin KM, Eils R, Autenrieth S, Janda A, Lehmann I, Binder M. Magalhães VG, et al. Among authors: debatin km. EMBO Rep. 2023 Dec 6;24(12):e57912. doi: 10.15252/embr.202357912. Epub 2023 Oct 11. EMBO Rep. 2023. PMID: 37818799 Free PMC article.
High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection.
Jacobsen EM, Fabricius D, Class M, Topfstedt F, Lorenzetti R, Janowska I, Schmidt F, Staniek J, Zernickel M, Stamminger T, Dietz AN, Zellmer A, Hecht M, Rauch P, Blum C, Ludwig C, Jahrsdörfer B, Schrezenmeier H, Heeg M, Mayer B, Seidel A, Groß R, Münch J, Kirchhoff F, Bode SFN, Strauss G, Renk H, Elling R, Stich M, Voll RE, Tönshof B, Franz AR, Henneke P, Debatin KM, Rizzi M, Janda A. Jacobsen EM, et al. Among authors: debatin km. Nat Commun. 2022 Nov 28;13(1):7315. doi: 10.1038/s41467-022-35055-1. Nat Commun. 2022. PMID: 36437276 Free PMC article.
Serum neutralizing capacity and T-cell response against the omicron BA.1 variant in seropositive children and their parents one year after SARS-CoV-2 infection.
Seidel A, Jacobsen EM, Fabricius D, Class M, Zernickel M, Blum C, Conzelmann C, Weil T, Groß R, Bode SFN, Renk H, Elling R, Stich M, Kirchhoff F, Debatin KM, Münch J, Janda A. Seidel A, et al. Among authors: debatin km. Front Pediatr. 2023 Mar 27;11:1020865. doi: 10.3389/fped.2023.1020865. eCollection 2023. Front Pediatr. 2023. PMID: 37051428 Free PMC article.
Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes.
Roos J, Zinngrebe J, Huber-Lang M, Lupu L, Schmidt MA, Strobel H, Westhoff MA, Stifel U, Gebhard F, Wabitsch M, Mollnes TE, Debatin KM, Halbgebauer R, Fischer-Posovszky P. Roos J, et al. Among authors: debatin km. Cell Death Dis. 2024 Apr 23;15(4):285. doi: 10.1038/s41419-024-06676-9. Cell Death Dis. 2024. PMID: 38653969 Free PMC article.
A partial human LCK defect causes a T cell immunodeficiency with intestinal inflammation.
Lui VG, Hoenig M, Cabrera-Martinez B, Baxter RM, Garcia-Perez JE, Bailey O, Acharya A, Lundquist K, Capera J, Matusewicz P, Hartl FA, D'Abramo M, Alba J, Jacobsen EM, Niewolik D, Lorenz M, Pannicke U, Schulz AS, Debatin KM, Schamel WW, Minguet S, Gumbart JC, Dustin ML, Cambier JC, Schwarz K, Hsieh EWY. Lui VG, et al. Among authors: debatin km. J Exp Med. 2024 Jan 1;221(1):e20230927. doi: 10.1084/jem.20230927. Epub 2023 Nov 14. J Exp Med. 2024. PMID: 37962568 Free PMC article.
529 results