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The genetic structure and adaptation of Andean highlanders and Amazonians are influenced by the interplay between geography and culture.
Borda V, Alvim I, Mendes M, Silva-Carvalho C, Soares-Souza GB, Leal TP, Furlan V, Scliar MO, Zamudio R, Zolini C, Araújo GS, Luizon MR, Padilla C, Cáceres O, Levano K, Sánchez C, Trujillo O, Flores-Villanueva PO, Dean M, Fuselli S, Machado M, Romero PE, Tassi F, Yeager M, O'Connor TD, Gilman RH, Tarazona-Santos E, Guio H. Borda V, et al. Among authors: dean m. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32557-32565. doi: 10.1073/pnas.2013773117. Epub 2020 Dec 4. Proc Natl Acad Sci U S A. 2020. PMID: 33277433 Free PMC article.
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
Gold B, Kirchhoff T, Stefanov S, Lautenberger J, Viale A, Garber J, Friedman E, Narod S, Olshen AB, Gregersen P, Kosarin K, Olsh A, Bergeron J, Ellis NA, Klein RJ, Clark AG, Norton L, Dean M, Boyd J, Offit K. Gold B, et al. Among authors: dean m. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4340-5. doi: 10.1073/pnas.0800441105. Epub 2008 Mar 7. Proc Natl Acad Sci U S A. 2008. PMID: 18326623 Free PMC article.
Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility.
Lou H, Yeager M, Li H, Bosquet JG, Hayes RB, Orr N, Yu K, Hutchinson A, Jacobs KB, Kraft P, Wacholder S, Chatterjee N, Feigelson HS, Thun MJ, Diver WR, Albanes D, Virtamo J, Weinstein S, Ma J, Gaziano JM, Stampfer M, Schumacher FR, Giovannucci E, Cancel-Tassin G, Cussenot O, Valeri A, Andriole GL, Crawford ED, Anderson SK, Tucker M, Hoover RN, Fraumeni JF Jr, Thomas G, Hunter DJ, Dean M, Chanock SJ. Lou H, et al. Among authors: dean m. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7933-8. doi: 10.1073/pnas.0902104106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383797 Free PMC article.
Mosaic chromosome 20q deletions are more frequent in the aging population.
Machiela MJ, Zhou W, Caporaso N, Dean M, Gapstur SM, Goldin L, Rothman N, Stevens VL, Yeager M, Chanock SJ. Machiela MJ, et al. Among authors: dean m. Blood Adv. 2017 Feb 13;1(6):380-385. doi: 10.1182/bloodadvances.2016003129. eCollection 2017 Feb 14. Blood Adv. 2017. PMID: 29296952 Free PMC article.
Genetic signatures of gene flow and malaria-driven natural selection in sub-Saharan populations of the "endemic Burkitt Lymphoma belt".
Gouveia MH, Bergen AW, Borda V, Nunes K, Leal TP, Ogwang MD, Yeboah ED, Mensah JE, Kinyera T, Otim I, Nabalende H, Legason ID, Mpoloka SW, Mokone GG, Kerchan P, Bhatia K, Reynolds SJ, Birtwum RB, Adjei AA, Tettey Y, Tay E, Hoover R, Pfeiffer RM, Biggar RJ, Goedert JJ, Prokunina-Olsson L, Dean M, Yeager M, Lima-Costa MF, Hsing AW, Tishkoff SA, Chanock SJ, Tarazona-Santos E, Mbulaiteye SM. Gouveia MH, et al. Among authors: dean m. PLoS Genet. 2019 Mar 8;15(3):e1008027. doi: 10.1371/journal.pgen.1008027. eCollection 2019 Mar. PLoS Genet. 2019. PMID: 30849090 Free PMC article.
Origins, Admixture Dynamics, and Homogenization of the African Gene Pool in the Americas.
Gouveia MH, Borda V, Leal TP, Moreira RG, Bergen AW, Kehdy FSG, Alvim I, Aquino MM, Araujo GS, Araujo NM, Furlan V, Liboredo R, Machado M, Magalhaes WCS, Michelin LA, Rodrigues MR, Rodrigues-Soares F, Sant Anna HP, Santolalla ML, Scliar MO, Soares-Souza G, Zamudio R, Zolini C, Bortolini MC, Dean M, Gilman RH, Guio H, Rocha J, Pereira AC, Barreto ML, Horta BL, Lima-Costa MF, Mbulaiteye SM, Chanock SJ, Tishkoff SA, Yeager M, Tarazona-Santos E. Gouveia MH, et al. Among authors: dean m. Mol Biol Evol. 2020 Jun 1;37(6):1647-1656. doi: 10.1093/molbev/msaa033. Mol Biol Evol. 2020. PMID: 32128591 Free PMC article.
Tracing the Distribution of European Lactase Persistence Genotypes Along the Americas.
Guimarães Alves AC, Sukow NM, Adelman Cipolla G, Mendes M, Leal TP, Petzl-Erler ML, Lehtonen Rodrigues Souza R, Rainha de Souza I, Sanchez C, Santolalla M, Loesch D, Dean M, Machado M, Moon JY, Kaplan R, North KE, Weiss S, Barreto ML, Lima-Costa MF, Guio H, Cáceres O, Padilla C, Tarazona-Santos E, Mata IF, Dieguez E, Raggio V, Lescano A, Tumas V, Borges V, Ferraz HB, Rieder CR, Schumacher-Schuh A, Santos-Lobato BL, Chana-Cuevas P, Fernandez W, Arboleda G, Arboleda H, Arboleda-Bustos CE, O'Connor TD, Beltrame MH, Borda V. Guimarães Alves AC, et al. Among authors: dean m. Front Genet. 2021 Sep 22;12:671079. doi: 10.3389/fgene.2021.671079. eCollection 2021. Front Genet. 2021. PMID: 34630506 Free PMC article.
Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Brazil.
Naslavsky MS, Scliar MO, Yamamoto GL, Wang JYT, Zverinova S, Karp T, Nunes K, Ceroni JRM, de Carvalho DL, da Silva Simões CE, Bozoklian D, Nonaka R, Dos Santos Brito Silva N, da Silva Souza A, de Souza Andrade H, Passos MRS, Castro CFB, Mendes-Junior CT, Mercuri RLV, Miller TLA, Buzzo JL, Rego FO, Araújo NM, Magalhães WCS, Mingroni-Netto RC, Borda V, Guio H, Rojas CP, Sanchez C, Caceres O, Dean M, Barreto ML, Lima-Costa MF, Horta BL, Tarazona-Santos E, Meyer D, Galante PAF, Guryev V, Castelli EC, Duarte YAO, Passos-Bueno MR, Zatz M. Naslavsky MS, et al. Among authors: dean m. Nat Commun. 2022 Mar 4;13(1):1004. doi: 10.1038/s41467-022-28648-3. Nat Commun. 2022. PMID: 35246524 Free PMC article.
1,605 results