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100 years of glucagon and 100 more.
Wewer Albrechtsen NJ, Holst JJ, Cherrington AD, Finan B, Gluud LL, Dean ED, Campbell JE, Bloom SR, Tan TM, Knop FK, Müller TD. Wewer Albrechtsen NJ, et al. Among authors: dean ed. Diabetologia. 2023 Aug;66(8):1378-1394. doi: 10.1007/s00125-023-05947-y. Epub 2023 Jun 27. Diabetologia. 2023. PMID: 37367959 Review.
Interrupted Glucagon Signaling Reveals Hepatic α Cell Axis and Role for L-Glutamine in α Cell Proliferation.
Dean ED, Li M, Prasad N, Wisniewski SN, Von Deylen A, Spaeth J, Maddison L, Botros A, Sedgeman LR, Bozadjieva N, Ilkayeva O, Coldren A, Poffenberger G, Shostak A, Semich MC, Aamodt KI, Phillips N, Yan H, Bernal-Mizrachi E, Corbin JD, Vickers KC, Levy SE, Dai C, Newgard C, Gu W, Stein R, Chen W, Powers AC. Dean ED, et al. Cell Metab. 2017 Jun 6;25(6):1362-1373.e5. doi: 10.1016/j.cmet.2017.05.011. Cell Metab. 2017. PMID: 28591638 Free PMC article.
Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.
Wang MY, Dean ED, Quittner-Strom E, Zhu Y, Chowdhury KH, Zhang Z, Zhao S, Li N, Ye R, Lee Y, Zhang Y, Chen S, Yu X, Leonard DC, Poffenberger G, Von Deylen A, McCorkle SK, Schlegel A, Sloop KW, Efanov AM, Gimeno RE, Scherer PE, Powers AC, Unger RH, Holland WL. Wang MY, et al. Among authors: dean ed. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2022142118. doi: 10.1073/pnas.2022142118. Proc Natl Acad Sci U S A. 2021. PMID: 33619103 Free PMC article.
Metabolic regulation of glucagon secretion.
Armour SL, Stanley JE, Cantley J, Dean ED, Knudsen JG. Armour SL, et al. Among authors: dean ed. J Endocrinol. 2023 Sep 8;259(1):e230081. doi: 10.1530/JOE-23-0081. Print 2023 Sep 1. J Endocrinol. 2023. PMID: 37523232 Free PMC article.
Glucagon: The Name Says It All, or Not!
Dean ED, Vuguin PM, Charron MJ. Dean ED, et al. Endocrinology. 2019 May 1;160(5):1359-1361. doi: 10.1210/en.2019-00251. Endocrinology. 2019. PMID: 31144717 Free PMC article. No abstract available.
Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2.
Spears E, Stanley JE, Shou M, Yin L, Li X, Dai C, Bradley A, Sellick K, Poffenberger G, Coate KC, Shrestha S, Jenkins R, Sloop KW, Wilson KT, Attie AD, Keller MP, Chen W, Powers AC, Dean ED. Spears E, et al. Among authors: dean ed. bioRxiv [Preprint]. 2023 Aug 14:2023.08.10.552656. doi: 10.1101/2023.08.10.552656. bioRxiv. 2023. PMID: 37645716 Free PMC article. Preprint.
Glucagon antagonism in islet cell proliferation.
Dean ED, Unger RH, Holland WL. Dean ED, et al. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):3006-3008. doi: 10.1073/pnas.1700468114. Epub 2017 Mar 10. Proc Natl Acad Sci U S A. 2017. PMID: 28283660 Free PMC article. No abstract available.
23 results