DePinho RA - Search Results

1

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.

Viale A, Pettazzoni P, Lyssiotis CA, Ying H, Sánchez N, Marchesini M, Carugo A, Green T, Seth S, Giuliani V, Kost-Alimova M, Muller F, Colla S, Nezi L, Genovese G, Deem AK, Kapoor A, Yao W, Brunetto E, Kang Y, Yuan M, Asara JM, Wang YA, Heffernan TP, Kimmelman AC, Wang H, Fleming JB, Cantley LC, DePinho RA, Draetta GF. Viale A, et al. Among authors: depinho ra. Nature. 2014 Oct 30;514(7524):628-32. doi: 10.1038/nature13611. Epub 2014 Aug 10. Nature. 2014. PMID: 25119024 Free PMC article.

2

Essential role for oncogenic Ras in tumour maintenance.

Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N, Shen Q, O'Hagan R, Pantginis J, Zhou H, Horner JW 2nd, Cordon-Cardo C, Yancopoulos GD, DePinho RA. Chin L, et al. Among authors: depinho ra. Nature. 1999 Jul 29;400(6743):468-72. doi: 10.1038/22788. Nature. 1999. PMID: 10440378

3

Gene-target recognition among members of the myc superfamily and implications for oncogenesis.

O'Hagan RC, Schreiber-Agus N, Chen K, David G, Engelman JA, Schwab R, Alland L, Thomson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. O'Hagan RC, et al. Among authors: depinho ra. Nat Genet. 2000 Feb;24(2):113-9. doi: 10.1038/72761. Nat Genet. 2000. PMID: 10655054

4

Mice without telomerase: what can they teach us about human cancer?

Artandi SE, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Nat Med. 2000 Aug;6(8):852-5. doi: 10.1038/78595. Nat Med. 2000. PMID: 10932211 Review.

5

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.

Artandi SE, Chang S, Lee SL, Alson S, Gottlieb GJ, Chin L, DePinho RA. Artandi SE, et al. Among authors: depinho ra. Nature. 2000 Aug 10;406(6796):641-5. doi: 10.1038/35020592. Nature. 2000. PMID: 10949306

6

The age of cancer.

DePinho RA. DePinho RA. Nature. 2000 Nov 9;408(6809):248-54. doi: 10.1038/35041694. Nature. 2000. PMID: 11089982 Review.

7

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.

Sharpless NE, Bardeesy N, Lee KH, Carrasco D, Castrillon DH, Aguirre AJ, Wu EA, Horner JW, DePinho RA. Sharpless NE, et al. Among authors: depinho ra. Nature. 2001 Sep 6;413(6851):86-91. doi: 10.1038/35092592. Nature. 2001. PMID: 11544531

8

Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation.

Bardeesy N, Sinha M, Hezel AF, Signoretti S, Hathaway NA, Sharpless NE, Loda M, Carrasco DR, DePinho RA. Bardeesy N, et al. Among authors: depinho ra. Nature. 2002 Sep 12;419(6903):162-7. doi: 10.1038/nature01045. Nature. 2002. PMID: 12226664 Free article.

9

Pancreatic cancer biology and genetics.

Bardeesy N, DePinho RA. Bardeesy N, et al. Among authors: depinho ra. Nat Rev Cancer. 2002 Dec;2(12):897-909. doi: 10.1038/nrc949. Nat Rev Cancer. 2002. PMID: 12459728 Review.

10

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing.

Wong KK, Maser RS, Bachoo RM, Menon J, Carrasco DR, Gu Y, Alt FW, DePinho RA. Wong KK, et al. Among authors: depinho ra. Nature. 2003 Feb 6;421(6923):643-8. doi: 10.1038/nature01385. Epub 2003 Jan 22. Nature. 2003. PMID: 12540856

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