DeMattos RB - Search Results

1

Melanoma-Secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis.

Kleffman K, Levinson G, Rose IVL, Blumenberg LM, Shadaloey SAA, Dhabaria A, Wong E, Galán-Echevarría F, Karz A, Argibay D, Von Itter R, Floristán A, Baptiste G, Eskow NM, Tranos JA, Chen J, Vega Y Saenz de Miera EC, Call M, Rogers R, Jour G, Wadghiri YZ, Osman I, Li YM, Mathews P, DeMattos RB, Ueberheide B, Ruggles KV, Liddelow SA, Schneider RJ, Hernando E. Kleffman K, et al. Among authors: demattos rb. Cancer Discov. 2022 May 2;12(5):1314-1335. doi: 10.1158/2159-8290.CD-21-1006. Cancer Discov. 2022. PMID: 35262173 Free PMC article.

2

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

Racke MM, Boone LI, Hepburn DL, Parsadainian M, Bryan MT, Ness DK, Piroozi KS, Jordan WH, Brown DD, Hoffman WP, Holtzman DM, Bales KR, Gitter BD, May PC, Paul SM, DeMattos RB. Racke MM, et al. Among authors: demattos rb. J Neurosci. 2005 Jan 19;25(3):629-36. doi: 10.1523/JNEUROSCI.4337-04.2005. J Neurosci. 2005. PMID: 15659599 Free PMC article.

3

Apolipoprotein E, amyloid, and Alzheimer disease.

Bales KR, Dodart JC, DeMattos RB, Holtzman DM, Paul SM. Bales KR, et al. Among authors: demattos rb. Mol Interv. 2002 Oct;2(6):363-75, 339. doi: 10.1124/mi.2.6.363. Mol Interv. 2002. PMID: 14993413 Review.

4

Apolipoprotein E dose-dependent modulation of beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

DeMattos RB. DeMattos RB. J Mol Neurosci. 2004;23(3):255-62. doi: 10.1385/JMN:23:3:255. J Mol Neurosci. 2004. PMID: 15181254 Review.

5

Pharmacokinetics and Pharmacodynamics of LY2599666, a PEG-Linked Antigen Binding Fragment that Targets Soluble Monomer Amyloid-β.

Li L, Zhen EY, Decker RL, Willis BA, Waters D, Liu P, Hake AM, Demattos RB, Ayan-Oshodi M. Li L, et al. Among authors: demattos rb. J Alzheimers Dis. 2019;68(1):137-144. doi: 10.3233/JAD-180925. J Alzheimers Dis. 2019. PMID: 30741684 Clinical Trial.

6

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. DeMattos RB, et al. Science. 2002 Mar 22;295(5563):2264-7. doi: 10.1126/science.1067568. Science. 2002. PMID: 11910111

7

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM. Dodart JC, et al. Among authors: demattos rb. Nat Neurosci. 2002 May;5(5):452-7. doi: 10.1038/nn842. Nat Neurosci. 2002. PMID: 11941374

8

Safety and changes in plasma and cerebrospinal fluid amyloid beta after a single administration of an amyloid beta monoclonal antibody in subjects with Alzheimer disease.

Siemers ER, Friedrich S, Dean RA, Gonzales CR, Farlow MR, Paul SM, Demattos RB. Siemers ER, et al. Among authors: demattos rb. Clin Neuropharmacol. 2010 Mar-Apr;33(2):67-73. doi: 10.1097/WNF.0b013e3181cb577a. Clin Neuropharmacol. 2010. PMID: 20375655 Clinical Trial.

9

A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice.

Demattos RB, Lu J, Tang Y, Racke MM, Delong CA, Tzaferis JA, Hole JT, Forster BM, McDonnell PC, Liu F, Kinley RD, Jordan WH, Hutton ML. Demattos RB, et al. Neuron. 2012 Dec 6;76(5):908-20. doi: 10.1016/j.neuron.2012.10.029. Neuron. 2012. PMID: 23217740 Free article.

10

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-beta.

Morikawa M, Fryer JD, Sullivan PM, Christopher EA, Wahrle SE, DeMattos RB, O'Dell MA, Fagan AM, Lashuel HA, Walz T, Asai K, Holtzman DM. Morikawa M, et al. Among authors: demattos rb. Neurobiol Dis. 2005 Jun-Jul;19(1-2):66-76. doi: 10.1016/j.nbd.2004.11.005. Neurobiol Dis. 2005. PMID: 15837562

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