DeGrado WF - Search Results

1

Self-assembling dipeptide antibacterial nanostructures with membrane disrupting activity.

Schnaider L, Brahmachari S, Schmidt NW, Mensa B, Shaham-Niv S, Bychenko D, Adler-Abramovich L, Shimon LJW, Kolusheva S, DeGrado WF, Gazit E. Schnaider L, et al. Among authors: degrado wf. Nat Commun. 2017 Nov 8;8(1):1365. doi: 10.1038/s41467-017-01447-x. Nat Commun. 2017. PMID: 29118336 Free PMC article.

2

Antibacterial mechanism of action of arylamide foldamers.

Mensa B, Kim YH, Choi S, Scott R, Caputo GA, DeGrado WF. Mensa B, et al. Among authors: degrado wf. Antimicrob Agents Chemother. 2011 Nov;55(11):5043-53. doi: 10.1128/AAC.05009-11. Epub 2011 Aug 15. Antimicrob Agents Chemother. 2011. PMID: 21844313 Free PMC article.

3

Influenza virus A M2 protein generates negative Gaussian membrane curvature necessary for budding and scission.

Schmidt NW, Mishra A, Wang J, DeGrado WF, Wong GC. Schmidt NW, et al. Among authors: degrado wf. J Am Chem Soc. 2013 Sep 18;135(37):13710-9. doi: 10.1021/ja400146z. Epub 2013 Sep 6. J Am Chem Soc. 2013. PMID: 23962302 Free PMC article.

4

Comparative mechanistic studies of brilacidin, daptomycin, and the antimicrobial peptide LL16.

Mensa B, Howell GL, Scott R, DeGrado WF. Mensa B, et al. Among authors: degrado wf. Antimicrob Agents Chemother. 2014 Sep;58(9):5136-45. doi: 10.1128/AAC.02955-14. Epub 2014 Jun 16. Antimicrob Agents Chemother. 2014. PMID: 24936592 Free PMC article.

5

The accommodation index measures the perturbation associated with insertions and deletions in coiled-coils: Application to understand signaling in histidine kinases.

Schmidt NW, Grigoryan G, DeGrado WF. Schmidt NW, et al. Among authors: degrado wf. Protein Sci. 2017 Mar;26(3):414-435. doi: 10.1002/pro.3095. Epub 2017 Feb 23. Protein Sci. 2017. PMID: 27977891 Free PMC article. Review.

6

Activation pH and Gating Dynamics of Influenza A M2 Proton Channel Revealed by Single-Molecule Spectroscopy.

Lin CW, Mensa B, Barniol-Xicota M, DeGrado WF, Gai F. Lin CW, et al. Among authors: degrado wf. Angew Chem Int Ed Engl. 2017 May 2;56(19):5283-5287. doi: 10.1002/anie.201701874. Epub 2017 Apr 4. Angew Chem Int Ed Engl. 2017. PMID: 28374543 Free PMC article.

7

A long-lived Aβ oligomer resistant to fibrillization.

Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. Nick M, et al. Among authors: degrado wf. Biopolymers. 2018 Aug;109(8):e23096. doi: 10.1002/bip.23096. Epub 2018 Jan 10. Biopolymers. 2018. PMID: 29319162 Free PMC article.

8

Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus.

Bhate MP, Lemmin T, Kuenze G, Mensa B, Ganguly S, Peters JM, Schmidt N, Pelton JG, Gross CA, Meiler J, DeGrado WF. Bhate MP, et al. Among authors: degrado wf. J Am Chem Soc. 2018 Jun 20;140(24):7471-7485. doi: 10.1021/jacs.7b09670. Epub 2018 Jun 9. J Am Chem Soc. 2018. PMID: 29771498 Free PMC article.

9

SNAC-tag for sequence-specific chemical protein cleavage.

Dang B, Mravic M, Hu H, Schmidt N, Mensa B, DeGrado WF. Dang B, et al. Among authors: degrado wf. Nat Methods. 2019 Apr;16(4):319-322. doi: 10.1038/s41592-019-0357-3. Epub 2019 Mar 25. Nat Methods. 2019. PMID: 30923372 Free PMC article.

10

Allosteric cooperation in a de novo-designed two-domain protein.

Pirro F, Schmidt N, Lincoff J, Widel ZX, Polizzi NF, Liu L, Therien MJ, Grabe M, Chino M, Lombardi A, DeGrado WF. Pirro F, et al. Among authors: degrado wf. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33246-33253. doi: 10.1073/pnas.2017062117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318174 Free PMC article.

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