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CDC7-independent G1/S transition revealed by targeted protein degradation.
Suski JM, Ratnayeke N, Braun M, Zhang T, Strmiska V, Michowski W, Can G, Simoneau A, Snioch K, Cup M, Sullivan CM, Wu X, Nowacka J, Branigan TB, Pack LR, DeCaprio JA, Geng Y, Zou L, Gygi SP, Walter JC, Meyer T, Sicinski P. Suski JM, et al. Among authors: decaprio ja. Nature. 2022 May;605(7909):357-365. doi: 10.1038/s41586-022-04698-x. Epub 2022 May 4. Nature. 2022. PMID: 35508654 Free PMC article.
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction.
Gao D, Wan L, Inuzuka H, Berg AH, Tseng A, Zhai B, Shaik S, Bennett E, Tron AE, Gasser JA, Lau A, Gygi SP, Harper JW, DeCaprio JA, Toker A, Wei W. Gao D, et al. Among authors: decaprio ja. Mol Cell. 2010 Sep 10;39(5):797-808. doi: 10.1016/j.molcel.2010.08.016. Mol Cell. 2010. PMID: 20832730 Free PMC article.
Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.
Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Zhang J, et al. Among authors: decaprio ja. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. Mol Cell. 2016. PMID: 27237051 Free PMC article.
Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.
Odajima J, Saini S, Jung P, Ndassa-Colday Y, Ficaro S, Geng Y, Marco E, Michowski W, Wang YE, DeCaprio JA, Litovchick L, Marto J, Sicinski P. Odajima J, et al. Among authors: decaprio ja. PLoS Genet. 2016 Nov 9;12(11):e1006429. doi: 10.1371/journal.pgen.1006429. eCollection 2016 Nov. PLoS Genet. 2016. PMID: 27828963 Free PMC article.
MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity.
Branigan TB, Kozono D, Schade AE, Deraska P, Rivas HG, Sambel L, Reavis HD, Shapiro GI, D'Andrea AD, DeCaprio JA. Branigan TB, et al. Among authors: decaprio ja. Cell Rep. 2021 Mar 2;34(9):108808. doi: 10.1016/j.celrep.2021.108808. Cell Rep. 2021. PMID: 33657372 Free PMC article.
219 results