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The DREAM complex mediates GIST cell quiescence and is a novel therapeutic target to enhance imatinib-induced apoptosis.
Boichuk S, Parry JA, Makielski KR, Litovchick L, Baron JL, Zewe JP, Wozniak A, Mehalek KR, Korzeniewski N, Seneviratne DS, Schöffski P, Debiec-Rychter M, DeCaprio JA, Duensing A. Boichuk S, et al. Among authors: decaprio ja. Cancer Res. 2013 Aug 15;73(16):5120-9. doi: 10.1158/0008-5472.CAN-13-0579. Epub 2013 Jun 20. Cancer Res. 2013. PMID: 23786773
A kinase shRNA screen links LATS2 and the pRB tumor suppressor.
Tschöp K, Conery AR, Litovchick L, Decaprio JA, Settleman J, Harlow E, Dyson N. Tschöp K, et al. Among authors: decaprio ja. Genes Dev. 2011 Apr 15;25(8):814-30. doi: 10.1101/gad.2000211. Genes Dev. 2011. PMID: 21498571 Free PMC article.
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor.
Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL, Adelmant G, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J, Marto JA, Hill DE, Cusick ME, Vidal M, Florens L, Washburn MP, Litovchick L, DeCaprio JA. Fine DA, et al. Among authors: decaprio ja. PLoS Pathog. 2012;8(10):e1002949. doi: 10.1371/journal.ppat.1002949. Epub 2012 Oct 18. PLoS Pathog. 2012. PMID: 23093934 Free PMC article.
Loss of the mammalian DREAM complex deregulates chondrocyte proliferation.
Forristal C, Henley SA, MacDonald JI, Bush JR, Ort C, Passos DT, Talluri S, Ishak CA, Thwaites MJ, Norley CJ, Litovchick L, DeCaprio JA, DiMattia G, Holdsworth DW, Beier F, Dick FA. Forristal C, et al. Among authors: decaprio ja. Mol Cell Biol. 2014 Jun;34(12):2221-34. doi: 10.1128/MCB.01523-13. Epub 2014 Apr 7. Mol Cell Biol. 2014. PMID: 24710275 Free PMC article.
219 results