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Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.
Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis C, Um SW, Kim DH, Ahn JM, DeBerardinis RJ, White MA, Minna JD, Yoo H. Lou TF, et al. Among authors: deberardinis rj. Cancer Prev Res (Phila). 2016 Jan;9(1):43-52. doi: 10.1158/1940-6207.CAPR-14-0287. Epub 2015 Oct 28. Cancer Prev Res (Phila). 2016. PMID: 26511490 Free PMC article.
Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Among authors: deberardinis rj. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.
Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.
Srivastava N, Kollipara RK, Singh DK, Sudderth J, Hu Z, Nguyen H, Wang S, Humphries CG, Carstens R, Huffman KE, DeBerardinis RJ, Kittler R. Srivastava N, et al. Among authors: deberardinis rj. Cell Metab. 2014 Oct 7;20(4):650-61. doi: 10.1016/j.cmet.2014.08.003. Epub 2014 Sep 25. Cell Metab. 2014. PMID: 25264247 Free PMC article.
NRF2 regulates serine biosynthesis in non-small cell lung cancer.
DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. DeNicola GM, et al. Among authors: deberardinis rj. Nat Genet. 2015 Dec;47(12):1475-81. doi: 10.1038/ng.3421. Epub 2015 Oct 19. Nat Genet. 2015. PMID: 26482881 Free PMC article.
Erratum: NRF2 regulates serine biosynthesis in non-small cell lung cancer.
DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC. DeNicola GM, et al. Among authors: deberardinis rj. Nat Genet. 2016 Apr;48(4):473. doi: 10.1038/ng0329-473a. Nat Genet. 2016. PMID: 27023779 No abstract available.
Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Padanad MS, Konstantinidou G, Venkateswaran N, Melegari M, Rindhe S, Mitsche M, Yang C, Batten K, Huffman KE, Liu J, Tang X, Rodriguez-Canales J, Kalhor N, Shay JW, Minna JD, McDonald J, Wistuba II, DeBerardinis RJ, Scaglioni PP. Padanad MS, et al. Among authors: deberardinis rj. Cell Rep. 2016 Aug 9;16(6):1614-1628. doi: 10.1016/j.celrep.2016.07.009. Epub 2016 Jul 28. Cell Rep. 2016. PMID: 27477280 Free PMC article.
Lipid sensing by mTOR complexes via de novo synthesis of phosphatidic acid.
Menon D, Salloum D, Bernfeld E, Gorodetsky E, Akselrod A, Frias MA, Sudderth J, Chen PH, DeBerardinis R, Foster DA. Menon D, et al. J Biol Chem. 2017 Apr 14;292(15):6303-6311. doi: 10.1074/jbc.M116.772988. Epub 2017 Feb 21. J Biol Chem. 2017. PMID: 28223357 Free PMC article.
284 results