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Pulmonary exposure of mice to ammonium perfluoro(2-methyl-3-oxahexanoate) (GenX) suppresses the innate immune response to carbon black nanoparticles and stimulates lung cell proliferation.
Lee HY, You DJ, Taylor-Just AJ, Linder KE, Atkins HM, Ralph LM, De la Cruz G, Bonner JC. Lee HY, et al. Among authors: de la cruz g. Inhal Toxicol. 2022;34(9-10):244-259. doi: 10.1080/08958378.2022.2086651. Epub 2022 Jun 15. Inhal Toxicol. 2022. PMID: 35704474 Free PMC article.
Adjuvant-dependent effects on the safety and efficacy of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus.
Heise M, Dillard J, Taft-Benz S, Knight A, Anderson E, Pressey K, Parotti B, Martinez S, Diaz J, Sarkar S, Madden E, De la Cruz G, Adams L, Dinnon K 3rd, Leist S, Martinez D, Schaefer A, Powers J, Yount B, Castillo I, Morales N, Burdick J, Evangelista MK, Ralph L, Pankow N, Linnertz C, Lakshmanane P, Montgomery S, Ferris M, Baric R, Baxter V. Heise M, et al. Among authors: de la cruz g. Res Sq [Preprint]. 2023 Oct 27:rs.3.rs-3401539. doi: 10.21203/rs.3.rs-3401539/v1. Res Sq. 2023. PMID: 37961507 Free PMC article. Preprint.
Adjuvant-dependent impact of inactivated SARS-CoV-2 vaccines during heterologous infection by a SARS-related coronavirus.
Dillard JA, Taft-Benz SA, Knight AC, Anderson EJ, Pressey KD, Parotti B, Martinez SA, Diaz JL, Sarkar S, Madden EA, De la Cruz G, Adams LE, Dinnon KH 3rd, Leist SR, Martinez DR, Schäfer A, Powers JM, Yount BL Jr, Castillo IN, Morales NL, Burdick J, Evangelista MKD, Ralph LM, Pankow NC, Linnertz CL, Lakshmanane P, Montgomery SA, Ferris MT, Baric RS, Baxter VK, Heise MT. Dillard JA, et al. Among authors: de la cruz g. Nat Commun. 2024 May 3;15(1):3738. doi: 10.1038/s41467-024-47450-x. Nat Commun. 2024. PMID: 38702297 Free PMC article.
SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice.
Dinnon KH 3rd, Leist SR, Okuda K, Dang H, Fritch EJ, Gully KL, De la Cruz G, Evangelista MD, Asakura T, Gilmore RC, Hawkins P, Nakano S, West A, Schäfer A, Gralinski LE, Everman JL, Sajuthi SP, Zweigart MR, Dong S, McBride J, Cooley MR, Hines JB, Love MK, Groshong SD, VanSchoiack A, Phelan SJ, Liang Y, Hether T, Leon M, Zumwalt RE, Barton LM, Duval EJ, Mukhopadhyay S, Stroberg E, Borczuk A, Thorne LB, Sakthivel MK, Lee YZ, Hagood JS, Mock JR, Seibold MA, O'Neal WK, Montgomery SA, Boucher RC, Baric RS. Dinnon KH 3rd, et al. Among authors: de la cruz g. Sci Transl Med. 2022 Sep 28;14(664):eabo5070. doi: 10.1126/scitranslmed.abo5070. Epub 2022 Sep 28. Sci Transl Med. 2022. PMID: 35857635 Free PMC article.
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice.
Martinez DR, Schäfer A, Leist SR, De la Cruz G, West A, Atochina-Vasserman EN, Lindesmith LC, Pardi N, Parks R, Barr M, Li D, Yount B, Saunders KO, Weissman D, Haynes BF, Montgomery SA, Baric RS. Martinez DR, et al. Among authors: de la cruz g. Science. 2021 Aug 27;373(6558):991-998. doi: 10.1126/science.abi4506. Epub 2021 Jun 22. Science. 2021. PMID: 34214046 Free PMC article.
Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.
Kato T, Asakura T, Edwards CE, Dang H, Mikami Y, Okuda K, Chen G, Sun L, Gilmore RC, Hawkins P, De la Cruz G, Cooley MR, Bailey AB, Hewitt SM, Chertow DS, Borczuk AC, Salvatore S, Martinez FJ, Thorne LB, Askin FB, Ehre C, Randell SH, O'Neal WK, Baric RS, Boucher RC. Kato T, et al. Among authors: de la cruz g. Am J Respir Crit Care Med. 2022 Dec 1;206(11):1336-1352. doi: 10.1164/rccm.202111-2606OC. Am J Respir Crit Care Med. 2022. PMID: 35816430 Free PMC article.
Mapping of susceptibility loci for Ebola virus pathogenesis in mice.
Schäfer A, Marzi A, Furuyama W, Catanzaro NJ, Nguyen C, Haddock E, Feldmann F, Meade-White K, Thomas T, Hubbard ML, Gully KL, Leist SR, Hock P, Bell TA, De la Cruz GE, Midkiff BR, Martinez DR, Shaw GD, Miller DR, Vernon MJ, Graham RL, Cowley DO, Montgomery SA, Schughart K, de Villena FPM, Wilkerson GK, Ferris MT, Feldmann H, Baric RS. Schäfer A, et al. Among authors: de la cruz ge. Cell Rep. 2024 Apr 21;43(5):114127. doi: 10.1016/j.celrep.2024.114127. Online ahead of print. Cell Rep. 2024. PMID: 38652660 Free article.
Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species.
Thompson CG, Rosen EP, Prince HMA, White N, Sykes C, de la Cruz G, Mathews M, Deleage C, Estes JD, Charlins P, Mulder LR, Kovarova M, Adamson L, Arora S, Dellon ES, Peery AF, Shaheen NJ, Gay C, Muddiman DC, Akkina R, Garcia JV, Luciw P, Kashuba ADM. Thompson CG, et al. Among authors: de la cruz g. Sci Transl Med. 2019 Jul 3;11(499):eaap8758. doi: 10.1126/scitranslmed.aap8758. Sci Transl Med. 2019. PMID: 31270274 Free PMC article. Clinical Trial.
A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Martinez DR, Schäfer A, Gobeil S, Li D, De la Cruz G, Parks R, Lu X, Barr M, Stalls V, Janowska K, Beaudoin E, Manne K, Mansouri K, Edwards RJ, Cronin K, Yount B, Anasti K, Montgomery SA, Tang J, Golding H, Shen S, Zhou T, Kwong PD, Graham BS, Mascola JR, Montefiori DC, Alam SM, Sempowski G, Sempowski GD, Khurana S, Wiehe K, Saunders KO, Acharya P, Haynes BF, Baric RS. Martinez DR, et al. Among authors: de la cruz g. Sci Transl Med. 2022 Jan 26;14(629):eabj7125. doi: 10.1126/scitranslmed.abj7125. Epub 2022 Jan 26. Sci Transl Med. 2022. PMID: 34726473 Free PMC article.
74 results