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Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.
Sacilotto N, Monteiro R, Fritzsche M, Becker PW, Sanchez-Del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S. Sacilotto N, et al. Among authors: de val s. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11893-8. doi: 10.1073/pnas.1300805110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818617 Free PMC article.
A polymorphic p53 response element in KIT ligand influences cancer risk and has undergone natural selection.
Zeron-Medina J, Wang X, Repapi E, Campbell MR, Su D, Castro-Giner F, Davies B, Peterse EF, Sacilotto N, Walker GJ, Terzian T, Tomlinson IP, Box NF, Meinshausen N, De Val S, Bell DA, Bond GL. Zeron-Medina J, et al. Among authors: de val s. Cell. 2013 Oct 10;155(2):410-22. doi: 10.1016/j.cell.2013.09.017. Cell. 2013. PMID: 24120139 Free PMC article.
MEF2 transcription factors are key regulators of sprouting angiogenesis.
Sacilotto N, Chouliaras KM, Nikitenko LL, Lu YW, Fritzsche M, Wallace MD, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris AL, Davies B, Bond GL, Bou-Gharios G, Schwarz JJ, De Val S. Sacilotto N, et al. Among authors: de val s. Genes Dev. 2016 Oct 15;30(20):2297-2309. doi: 10.1101/gad.290619.116. Genes Dev. 2016. PMID: 27898394 Free PMC article.
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: de val s. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: de val s. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Development. 2017. PMID: 28619820 Free PMC article.
42 results