De S - Search Results

1

IMPACT: a whole-exome sequencing analysis pipeline for integrating molecular profiles with actionable therapeutics in clinical samples.

Hintzsche J, Kim J, Yadav V, Amato C, Robinson SE, Seelenfreund E, Shellman Y, Wisell J, Applegate A, McCarter M, Box N, Tentler J, De S, Robinson WA, Tan AC. Hintzsche J, et al. Among authors: de s. J Am Med Inform Assoc. 2016 Jul;23(4):721-30. doi: 10.1093/jamia/ocw022. Epub 2016 Mar 28. J Am Med Inform Assoc. 2016. PMID: 27026619 Free PMC article.

2

An assessment of computational methods for estimating purity and clonality using genomic data derived from heterogeneous tumor tissue samples.

Yadav VK, De S. Yadav VK, et al. Among authors: de s. Brief Bioinform. 2015 Mar;16(2):232-41. doi: 10.1093/bib/bbu002. Epub 2014 Feb 20. Brief Bioinform. 2015. PMID: 24562872 Free PMC article. Review.

3

Signatures of accelerated somatic evolution in gene promoters in multiple cancer types.

Smith KS, Yadav VK, Pedersen BS, Shaknovich R, Geraci MW, Pollard KS, De S. Smith KS, et al. Among authors: de s. Nucleic Acids Res. 2015 Jun 23;43(11):5307-17. doi: 10.1093/nar/gkv419. Epub 2015 May 1. Nucleic Acids Res. 2015. PMID: 25934800 Free PMC article.

4

SomVarIUS: somatic variant identification from unpaired tissue samples.

Smith KS, Yadav VK, Pei S, Pollyea DA, Jordan CT, De S. Smith KS, et al. Among authors: de s. Bioinformatics. 2016 Mar 15;32(6):808-13. doi: 10.1093/bioinformatics/btv685. Epub 2015 Nov 20. Bioinformatics. 2016. PMID: 26589277

5

Expression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer.

Poczobutt JM, De S, Yadav VK, Nguyen TT, Li H, Sippel TR, Weiser-Evans MC, Nemenoff RA. Poczobutt JM, et al. Among authors: de s. J Immunol. 2016 Mar 15;196(6):2847-59. doi: 10.4049/jimmunol.1502364. Epub 2016 Feb 12. J Immunol. 2016. PMID: 26873985 Free PMC article.

6

The landscape of somatic mutations in protein coding genes in apparently benign human tissues carries signatures of relaxed purifying selection.

Yadav VK, DeGregori J, De S. Yadav VK, et al. Among authors: de s. Nucleic Acids Res. 2016 Mar 18;44(5):2075-84. doi: 10.1093/nar/gkw086. Epub 2016 Feb 15. Nucleic Acids Res. 2016. PMID: 26883632 Free PMC article.

7

Significance of duon mutations in cancer genomes.

Yadav VK, Smith KS, Flinders C, Mumenthaler SM, De S. Yadav VK, et al. Among authors: de s. Sci Rep. 2016 Jun 8;6:27437. doi: 10.1038/srep27437. Sci Rep. 2016. PMID: 27272679 Free PMC article.

8

Copy neutral loss of heterozygosity is more frequent in older ovarian cancer patients.

Pedersen BS, Konstantinopoulos PA, Spillman MA, De S. Pedersen BS, et al. Among authors: de s. Genes Chromosomes Cancer. 2013 Sep;52(9):794-801. doi: 10.1002/gcc.22075. Epub 2013 May 28. Genes Chromosomes Cancer. 2013. PMID: 23716468 Free PMC article.

9

Patterns of somatically acquired amplifications and deletions in apparently normal tissues of ovarian cancer patients.

Aghili L, Foo J, DeGregori J, De S. Aghili L, et al. Among authors: de s. Cell Rep. 2014 May 22;7(4):1310-9. doi: 10.1016/j.celrep.2014.03.071. Epub 2014 May 1. Cell Rep. 2014. PMID: 24794429 Free PMC article.

10

Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.

Pei S, Minhajuddin M, D'Alessandro A, Nemkov T, Stevens BM, Adane B, Khan N, Hagen FK, Yadav VK, De S, Ashton JM, Hansen KC, Gutman JA, Pollyea DA, Crooks PA, Smith C, Jordan CT. Pei S, et al. Among authors: de s. J Biol Chem. 2016 Oct 14;291(42):21984-22000. doi: 10.1074/jbc.M116.750653. Epub 2016 Aug 29. J Biol Chem. 2016. PMID: 27573247 Free PMC article.

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