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Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment.
Bertoni A, Penco F, Mollica H, Bocca P, Prigione I, Corcione A, Cangelosi D, Schena F, Del Zotto G, Amaro A, Paladino N, Pontali E, Feasi M, Signa S, Bustaffa M, Caorsi R, Palmeri S, Contini P, De Palma R, Pfeffer U, Uva P, Rubartelli A, Gattorno M, Volpi S. Bertoni A, et al. Among authors: de palma r. J Allergy Clin Immunol. 2022 Oct;150(4):796-805. doi: 10.1016/j.jaci.2022.05.029. Epub 2022 Jul 11. J Allergy Clin Immunol. 2022. PMID: 35835255 Free PMC article.
Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.
Harb H, Benamar M, Lai PS, Contini P, Griffith JW, Crestani E, Schmitz-Abe K, Chen Q, Fong J, Marri L, Filaci G, Del Zotto G, Pishesha N, Kolifrath S, Broggi A, Ghosh S, Gelmez MY, Oktelik FB, Cetin EA, Kiykim A, Kose M, Wang Z, Cui Y, Yu XG, Li JZ, Berra L, Stephen-Victor E, Charbonnier LM, Zanoni I, Ploegh H, Deniz G, De Palma R, Chatila TA. Harb H, et al. Among authors: de palma r. Immunity. 2021 Jun 8;54(6):1186-1199.e7. doi: 10.1016/j.immuni.2021.04.002. Epub 2021 Apr 28. Immunity. 2021. PMID: 33915108 Free PMC article.
Preservation of clonal heterogeneity of the Pneumocystis carinii-specific CD4 T cell repertoire in HIV infected, asymptomatic individuals.
Li Pira G, Fenoglio D, Bottone L, Terranova P, Pontali E, Caroli F, Seri M, Cailliez JC, Koopman G, Accolla R, del Galdo F, Abbate G, de Palma R, Manca F. Li Pira G, et al. Among authors: de palma r. Clin Exp Immunol. 2002 Apr;128(1):155-62. doi: 10.1046/j.1365-2249.2002.01799.x. Clin Exp Immunol. 2002. PMID: 11982603 Free PMC article.
Characterization of T lymphocytes in severe COVID-19 patients.
Fenoglio D, Dentone C, Parodi A, Di Biagio A, Bozzano F, Vena A, Fabbi M, Ferrera F, Altosole T, Bruzzone B, Giacomini M, Pelosi P, De Maria A, Bassetti M, De Palma R, Filaci G. Fenoglio D, et al. Among authors: de maria a, de palma r. J Med Virol. 2021 Sep;93(9):5608-5613. doi: 10.1002/jmv.27037. Epub 2021 May 3. J Med Virol. 2021. PMID: 33913544 Free PMC article.
Analysis of the antigen specific T cell repertoires in HIV infection.
Li Pira G, Bottone L, Fenoglio D, Terranova P, Pontali E, Ivaldi F, Del Galdo F, Mortara L, Loregian A, Palù G, Kunkl A, Accolla R, De Palma R, Manca F. Li Pira G, et al. Among authors: de palma r. Immunol Lett. 2001 Nov 1;79(1-2):85-91. doi: 10.1016/s0165-2478(01)00269-3. Immunol Lett. 2001. PMID: 11595293
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial.
Perrone F, Piccirillo MC, Ascierto PA, Salvarani C, Parrella R, Marata AM, Popoli P, Ferraris L, Marrocco-Trischitta MM, Ripamonti D, Binda F, Bonfanti P, Squillace N, Castelli F, Muiesan ML, Lichtner M, Calzetti C, Salerno ND, Atripaldi L, Cascella M, Costantini M, Dolci G, Facciolongo NC, Fraganza F, Massari M, Montesarchio V, Mussini C, Negri EA, Botti G, Cardone C, Gargiulo P, Gravina A, Schettino C, Arenare L, Chiodini P, Gallo C; TOCIVID-19 investigators, Italy. Perrone F, et al. J Transl Med. 2020 Oct 21;18(1):405. doi: 10.1186/s12967-020-02573-9. J Transl Med. 2020. PMID: 33087150 Free PMC article. Clinical Trial.
Editorial: Etiopathogenesis of Systemic Sclerosis: An Update.
Stifano G, De Palma R. Stifano G, et al. Among authors: de palma r. Front Immunol. 2021 Mar 22;12:663381. doi: 10.3389/fimmu.2021.663381. eCollection 2021. Front Immunol. 2021. PMID: 33828566 Free PMC article. No abstract available.
Extensive activation, tissue trafficking, turnover and functional impairment of NK cells in COVID-19 patients at disease onset associates with subsequent disease severity.
Bozzano F, Dentone C, Perrone C, Di Biagio A, Fenoglio D, Parodi A, Mikulska M, Bruzzone B, Giacobbe DR, Vena A, Taramasso L, Nicolini L, Patroniti N, Pelosi P, Gratarola A, De Palma R, Filaci G, Bassetti M, De Maria A; GECOVID study group. Bozzano F, et al. Among authors: de maria a, de palma r. PLoS Pathog. 2021 Apr 16;17(4):e1009448. doi: 10.1371/journal.ppat.1009448. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33861802 Free PMC article.
475 results