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Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage.
Billiet L, De Cock L, Sanchez Sanchez G, Mayer RL, Goetgeluk G, De Munter S, Pille M, Ingels J, Jansen H, Weening K, Pascal E, Raes K, Bonte S, Kerre T, Vandamme N, Seurinck R, Roels J, Lavaert M, Van Nieuwerburgh F, Leclercq G, Taghon T, Impens F, Menten B, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: de munter s. J Exp Med. 2023 Jun 5;220(6):e20220942. doi: 10.1084/jem.20220942. Epub 2023 Mar 20. J Exp Med. 2023. PMID: 36939517 Free PMC article.
Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities.
Van Caeneghem Y, De Munter S, Tieppo P, Goetgeluk G, Weening K, Verstichel G, Bonte S, Taghon T, Leclercq G, Kerre T, Debets R, Vermijlen D, Abken H, Vandekerckhove B. Van Caeneghem Y, et al. Among authors: de munter s. Oncoimmunology. 2017 Jan 19;6(3):e1283460. doi: 10.1080/2162402X.2017.1283460. eCollection 2017. Oncoimmunology. 2017. PMID: 28405508 Free PMC article.
The checkpoint for agonist selection precedes conventional selection in human thymus.
Verstichel G, Vermijlen D, Martens L, Goetgeluk G, Brouwer M, Thiault N, Van Caeneghem Y, De Munter S, Weening K, Bonte S, Leclercq G, Taghon T, Kerre T, Saeys Y, Van Dorpe J, Cheroutre H, Vandekerckhove B. Verstichel G, et al. Among authors: de munter s. Sci Immunol. 2017 Feb 24;2(8):eaah4232. doi: 10.1126/sciimmunol.aah4232. Sci Immunol. 2017. PMID: 28783686 Free PMC article.
Nanobody Based Dual Specific CARs.
De Munter S, Ingels J, Goetgeluk G, Bonte S, Pille M, Weening K, Kerre T, Abken H, Vandekerckhove B. De Munter S, et al. Int J Mol Sci. 2018 Jan 30;19(2):403. doi: 10.3390/ijms19020403. Int J Mol Sci. 2018. PMID: 29385713 Free PMC article.
TARP is an immunotherapeutic target in acute myeloid leukemia expressed in the leukemic stem cell compartment.
Depreter B, Weening KE, Vandepoele K, Essand M, De Moerloose B, Themeli M, Cloos J, Hanekamp D, Moors I, D'hont I, Denys B, Uyttebroeck A, Van Damme A, Dedeken L, Snauwaert S, Goetgeluk G, De Munter S, Kerre T, Vandekerckhove B, Lammens T, Philippé J. Depreter B, et al. Among authors: de munter s, de moerloose b. Haematologica. 2020 May;105(5):1306-1316. doi: 10.3324/haematol.2019.222612. Epub 2019 Aug 1. Haematologica. 2020. PMID: 31371409 Free PMC article.
Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly.
De Munter S, Van Parys A, Bral L, Ingels J, Goetgeluk G, Bonte S, Pille M, Billiet L, Weening K, Verhee A, Van der Heyden J, Taghon T, Leclercq G, Kerre T, Tavernier J, Vandekerckhove B. De Munter S, et al. Int J Mol Sci. 2020 Jan 30;21(3):883. doi: 10.3390/ijms21030883. Int J Mol Sci. 2020. PMID: 32019116 Free PMC article.
Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.
Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, Kerre T, Taghon T, Leclercq G, Vandekerckhove B. Billiet L, et al. Among authors: de munter s, de cock l. Int J Mol Sci. 2020 Nov 20;21(22):8785. doi: 10.3390/ijms21228785. Int J Mol Sci. 2020. PMID: 33233766 Free PMC article.
In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality.
Bonte S, de Munter S, Billiet L, Goetgeluk G, Ingels J, Jansen H, Pille M, de Cock L, Weening K, Taghon T, Leclercq G, Vandekerckhove B, Kerre T. Bonte S, et al. Among authors: de munter s. Oncoimmunology. 2021 Jul 25;10(1):1954800. doi: 10.1080/2162402X.2021.1954800. eCollection 2021. Oncoimmunology. 2021. PMID: 34367734 Free PMC article.
36 results