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Page 1
Tumor Testing and Genetic Analysis to Identify Lynch Syndrome Patients in an Italian Colorectal Cancer Cohort.
Pantaleo A, Forte G, Cariola F, Valentini AM, Fasano C, Sanese P, Grossi V, Buonadonna AL, De Marco K, Lepore Signorile M, Guglielmi AF, Manghisi A, Gigante G, Armentano R, Disciglio V, Simone C. Pantaleo A, et al. Among authors: de marco k. Cancers (Basel). 2023 Oct 19;15(20):5061. doi: 10.3390/cancers15205061. Cancers (Basel). 2023. PMID: 37894428 Free PMC article.
Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality.
Sanese P, Fasano C, Buscemi G, Bottino C, Corbetta S, Fabini E, Silvestri V, Valentini V, Disciglio V, Forte G, Lepore Signorile M, De Marco K, Bertora S, Grossi V, Guven U, Porta N, Di Maio V, Manoni E, Giannelli G, Bartolini M, Del Rio A, Caretti G, Ottini L, Simone C. Sanese P, et al. Among authors: de marco k. iScience. 2020 Oct 7;23(10):101604. doi: 10.1016/j.isci.2020.101604. eCollection 2020 Oct 23. iScience. 2020. PMID: 33205017 Free PMC article.
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids.
Lepore Signorile M, Grossi V, Di Franco S, Forte G, Disciglio V, Fasano C, Sanese P, De Marco K, Susca FC, Mangiapane LR, Nicotra A, Di Carlo G, Dituri F, Giannelli G, Ingravallo G, Canettieri G, Stassi G, Simone C. Lepore Signorile M, et al. Among authors: de marco k. Cell Death Dis. 2021 Mar 25;12(4):316. doi: 10.1038/s41419-021-03572-4. Cell Death Dis. 2021. PMID: 33767160 Free PMC article.
A novel STK11 gene mutation (c.388dupG, p.Glu130Glyfs∗33) in a Peutz-Jeghers family and evidence of higher gastric cancer susceptibility associated with alterations in STK11 region aa 107-170.
Forte G, Cariola F, De Marco K, Manghisi A, Guglielmi FA, Armentano R, Lippolis G, Giorgio P, Simone C, Disciglio V. Forte G, et al. Among authors: de marco k. Genes Dis. 2021 Nov 19;9(2):288-291. doi: 10.1016/j.gendis.2021.11.002. eCollection 2022 Mar. Genes Dis. 2021. PMID: 35224145 Free PMC article. No abstract available.
Identifying novel SMYD3 interactors on the trail of cancer hallmarks.
Fasano C, Lepore Signorile M, De Marco K, Forte G, Sanese P, Grossi V, Simone C. Fasano C, et al. Among authors: de marco k. Comput Struct Biotechnol J. 2022 Apr 11;20:1860-1875. doi: 10.1016/j.csbj.2022.03.037. eCollection 2022. Comput Struct Biotechnol J. 2022. PMID: 35495117 Free PMC article.
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3.
Parenti MD, Naldi M, Manoni E, Fabini E, Cederfelt D, Talibov VO, Gressani V, Guven U, Grossi V, Fasano C, Sanese P, De Marco K, Shtil AA, Kurkin AV, Altieri A, Danielson UH, Caretti G, Simone C, Varchi G, Bartolini M, Del Rio A. Parenti MD, et al. Among authors: de marco k. Eur J Med Chem. 2022 Dec 5;243:114683. doi: 10.1016/j.ejmech.2022.114683. Epub 2022 Sep 8. Eur J Med Chem. 2022. PMID: 36116234
c-MYC Protein Stability Is Sustained by MAPKs in Colorectal Cancer.
Lepore Signorile M, Grossi V, Fasano C, Forte G, Disciglio V, Sanese P, De Marco K, La Rocca F, Armentano R, Valentini AM, Giannelli G, Simone C. Lepore Signorile M, et al. Among authors: de marco k. Cancers (Basel). 2022 Oct 4;14(19):4840. doi: 10.3390/cancers14194840. Cancers (Basel). 2022. PMID: 36230763 Free PMC article.
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes.
Forte G, Cariola F, Buonadonna AL, Guglielmi AF, Manghisi A, De Marco K, Grossi V, Fasano C, Lepore Signorile M, Sanese P, Bagnulo R, Resta N, Disciglio V, Simone C. Forte G, et al. Among authors: de marco k. Genes Dis. 2022 Dec 27;10(4):1187-1189. doi: 10.1016/j.gendis.2022.11.017. eCollection 2023 Jul. Genes Dis. 2022. PMID: 37397536 Free PMC article. No abstract available.
80 results