De Magis A - Search Results

1

UV-induced G4 DNA structures recruit ZRF1 which prevents UV-induced senescence.

De Magis A, Limmer M, Mudiyam V, Monchaud D, Juranek S, Paeschke K. De Magis A, et al. Nat Commun. 2023 Oct 23;14(1):6705. doi: 10.1038/s41467-023-42494-x. Nat Commun. 2023. PMID: 37872164 Free PMC article.

2

DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions.

Sauer M, Juranek SA, Marks J, De Magis A, Kazemier HG, Hilbig D, Benhalevy D, Wang X, Hafner M, Paeschke K. Sauer M, et al. Among authors: de magis a. Nat Commun. 2019 Jun 3;10(1):2421. doi: 10.1038/s41467-019-10432-5. Nat Commun. 2019. PMID: 31160600 Free PMC article.

3

Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair.

De Magis A, Götz S, Hajikazemi M, Fekete-Szücs E, Caterino M, Juranek S, Paeschke K. De Magis A, et al. Nat Commun. 2020 Aug 6;11(1):3907. doi: 10.1038/s41467-020-17701-8. Nat Commun. 2020. PMID: 32764578 Free PMC article.

4

The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.

Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, Das SR, Paeschke K, Roberts SA, VanDemark AP, Bernstein KA. Rosenbaum JC, et al. Among authors: de magis a. Nat Commun. 2019 Aug 5;10(1):3515. doi: 10.1038/s41467-019-11374-8. Nat Commun. 2019. PMID: 31383866 Free PMC article.

5

BG-flow, a new flow cytometry tool for G-quadruplex quantification in fixed cells.

De Magis A, Kastl M, Brossart P, Heine A, Paeschke K. De Magis A, et al. BMC Biol. 2021 Mar 11;19(1):45. doi: 10.1186/s12915-021-00986-6. BMC Biol. 2021. PMID: 33706790 Free PMC article.

6

DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells.

De Magis A, Manzo SG, Russo M, Marinello J, Morigi R, Sordet O, Capranico G. De Magis A, et al. Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):816-825. doi: 10.1073/pnas.1810409116. Epub 2018 Dec 27. Proc Natl Acad Sci U S A. 2019. PMID: 30591567 Free PMC article.

7

TMPRSS2 isoform 1 downregulation by G-quadruplex stabilization induces SARS-CoV-2 replication arrest.

De Magis A, Schult P, Schönleber A, Linke R, Ludwig KU, Kümmerer BM, Paeschke K. De Magis A, et al. BMC Biol. 2024 Jan 8;22(1):5. doi: 10.1186/s12915-023-01805-w. BMC Biol. 2024. PMID: 38185627 Free PMC article.

8

Discovery of the first dual G-triplex/G-quadruplex stabilizing compound: a new opportunity in the targeting of G-rich DNA structures?

Amato J, Pagano A, Cosconati S, Amendola G, Fotticchia I, Iaccarino N, Marinello J, De Magis A, Capranico G, Novellino E, Pagano B, Randazzo A. Amato J, et al. Among authors: de magis a. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1271-1280. doi: 10.1016/j.bbagen.2016.11.008. Epub 2016 Nov 9. Biochim Biophys Acta Gen Subj. 2017. PMID: 27836755

9

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives.

Amato J, Morigi R, Pagano B, Pagano A, Ohnmacht S, De Magis A, Tiang YP, Capranico G, Locatelli A, Graziadio A, Leoni A, Rambaldi M, Novellino E, Neidle S, Randazzo A. Amato J, et al. Among authors: de magis a. J Med Chem. 2016 Jun 23;59(12):5706-20. doi: 10.1021/acs.jmedchem.6b00129. Epub 2016 Jun 6. J Med Chem. 2016. PMID: 27223049

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