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MEK1/2 inhibition decreases pro-inflammatory responses in macrophages from people with cystic fibrosis and mitigates severity of illness in experimental murine methicillin-resistant Staphylococcus aureus infection.
De M, Serpa G, Zuiker E, Hisert KB, Liles WC, Manicone AM, Hemann EA, Long ME. De M, et al. Front Cell Infect Microbiol. 2024 Jan 30;14:1275940. doi: 10.3389/fcimb.2024.1275940. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38352056 Free PMC article.
IFN-λ3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans.
De M, Sukla S, Bharatiya S, Keshri S, Roy DG, Roy S, Dutta D, Saha S, Ejazi SA, Ravichandiran V, Ali N, Chatterjee M, Chinnaswamy S. De M, et al. Infect Immun. 2024 Feb 13;92(2):e0050423. doi: 10.1128/iai.00504-23. Epub 2024 Jan 9. Infect Immun. 2024. PMID: 38193711 Free PMC article.
368 results