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Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells.
Di Martile M, Desideri M, De Luca T, Gabellini C, Buglioni S, Eramo A, Sette G, Milella M, Rotili D, Mai A, Carradori S, Secci D, De Maria R, Del Bufalo D, Trisciuoglio D. Di Martile M, et al. Among authors: de maria r, de luca t. Oncotarget. 2016 Mar 8;7(10):11332-48. doi: 10.18632/oncotarget.7238. Oncotarget. 2016. PMID: 26870991 Free PMC article.
The thiazole derivative CPTH6 impairs autophagy.
Ragazzoni Y, Desideri M, Gabellini C, De Luca T, Carradori S, Secci D, Nescatelli R, Candiloro A, Condello M, Meschini S, Del Bufalo D, Trisciuoglio D. Ragazzoni Y, et al. Among authors: de luca t. Cell Death Dis. 2013 Mar 7;4(3):e524. doi: 10.1038/cddis.2013.53. Cell Death Dis. 2013. PMID: 23470531 Free PMC article.
Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer.
Del Bufalo D, Desideri M, De Luca T, Di Martile M, Gabellini C, Monica V, Busso S, Eramo A, De Maria R, Milella M, Trisciuoglio D. Del Bufalo D, et al. Among authors: de maria r, de luca t. Mol Cancer. 2014 Oct 9;13:230. doi: 10.1186/1476-4598-13-230. Mol Cancer. 2014. PMID: 25301686 Free PMC article.
miR-211 and MITF modulation by Bcl-2 protein in melanoma cells.
De Luca T, Pelosi A, Trisciuoglio D, D'Aguanno S, Desideri M, Farini V, Di Martile M, Bellei B, Tupone MG, Candiloro A, Regazzo G, Rizzo MG, Del Bufalo D. De Luca T, et al. Mol Carcinog. 2016 Dec;55(12):2304-2312. doi: 10.1002/mc.22437. Epub 2015 Nov 24. Mol Carcinog. 2016. PMID: 26599548
PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.
Milella M, Falcone I, Conciatori F, Matteoni S, Sacconi A, De Luca T, Bazzichetto C, Corbo V, Simbolo M, Sperduti I, Benfante A, Del Curatolo A, Cesta Incani U, Malusa F, Eramo A, Sette G, Scarpa A, Konopleva M, Andreeff M, McCubrey JA, Blandino G, Todaro M, Stassi G, De Maria R, Cognetti F, Del Bufalo D, Ciuffreda L. Milella M, et al. Among authors: de maria r, de luca t. Sci Rep. 2017 Feb 21;7:43013. doi: 10.1038/srep43013. Sci Rep. 2017. PMID: 28220839 Free PMC article.
105 results