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Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function.
D'Hoker J, De Leu N, Heremans Y, Baeyens L, Minami K, Ying C, Lavens A, Chintinne M, Stangé G, Magenheim J, Swisa A, Martens G, Pipeleers D, van de Casteele M, Seino S, Keshet E, Dor Y, Heimberg H. D'Hoker J, et al. Among authors: de leu n. Diabetes. 2013 Dec;62(12):4165-73. doi: 10.2337/db12-1827. Epub 2013 Aug 23. Diabetes. 2013. PMID: 23974922 Free PMC article.
Reversal of hyperglycemia in diabetic mice by a marginal islet mass together with human blood outgrowth endothelial cells is independent of the delivery technique and blood clot-induced processes.
Coppens V, Heremans Y, Leuckx G, Suenens K, Jacobs-Tulleneers-Thevissen D, Verdonck K, Luttun A, Heimberg H, De Leu N. Coppens V, et al. Among authors: de leu n. Islets. 2013 Sep-Dec;5(5):196-200. doi: 10.4161/isl.26778. Epub 2013 Nov 8. Islets. 2013. PMID: 24213480 Free PMC article.
Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas.
Van Gassen N, Van Overmeire E, Leuckx G, Heremans Y, De Groef S, Cai Y, Elkrim Y, Gysemans C, Stijlemans B, Van de Casteele M, De Baetselier P, De Leu N, Heimberg H, Van Ginderachter JA. Van Gassen N, et al. Among authors: de groef s, de baetselier p, de leu n. Eur J Immunol. 2015 May;45(5):1482-93. doi: 10.1002/eji.201445013. Epub 2015 Mar 19. Eur J Immunol. 2015. PMID: 25645754 Free article.
Concise Review: Macrophages: Versatile Gatekeepers During Pancreatic β-Cell Development, Injury, and Regeneration.
Van Gassen N, Staels W, Van Overmeire E, De Groef S, Sojoodi M, Heremans Y, Leuckx G, Van de Casteele M, Van Ginderachter JA, Heimberg H, De Leu N. Van Gassen N, et al. Among authors: de groef s, de leu n. Stem Cells Transl Med. 2015 Jun;4(6):555-63. doi: 10.5966/sctm.2014-0272. Epub 2015 Apr 6. Stem Cells Transl Med. 2015. PMID: 25848123 Free PMC article. Review.
28 results