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Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer.
Basile A, De Marco M, Festa M, Falco A, Iorio V, Guerriero L, Eletto D, Rea D, Arra C, Lamolinara A, Ballerini P, Damiani V, Rosati A, Sala G, Turco MC, Marzullo L, De Laurenzi V. Basile A, et al. Among authors: de marco m, de laurenzi v. Mol Oncol. 2019 Jun;13(6):1388-1399. doi: 10.1002/1878-0261.12492. Epub 2019 May 17. Mol Oncol. 2019. PMID: 30973679 Free PMC article.
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth.
Chiappetta G, Basile A, Barbieri A, Falco A, Rosati A, Festa M, Pasquinelli R, Califano D, Palma G, Costanzo R, Barcaroli D, Capunzo M, Franco R, Rocco G, Pascale M, Turco MC, De Laurenzi V, Arra C. Chiappetta G, et al. Among authors: de laurenzi v. Oncotarget. 2014 Aug 30;5(16):6846-53. doi: 10.18632/oncotarget.2261. Oncotarget. 2014. PMID: 25149536 Free PMC article.
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.
Rosati A, Basile A, D'Auria R, d'Avenia M, De Marco M, Falco A, Festa M, Guerriero L, Iorio V, Parente R, Pascale M, Marzullo L, Franco R, Arra C, Barbieri A, Rea D, Menichini G, Hahne M, Bijlsma M, Barcaroli D, Sala G, di Mola FF, di Sebastiano P, Todoric J, Antonucci L, Corvest V, Jawhari A, Firpo MA, Tuveson DA, Capunzo M, Karin M, De Laurenzi V, Turco MC. Rosati A, et al. Among authors: de marco m, de laurenzi v. Nat Commun. 2015 Nov 2;6:8695. doi: 10.1038/ncomms9695. Nat Commun. 2015. PMID: 26522614 Free PMC article.
BAG3 Protein Is Over-Expressed in Endometrioid Endometrial Adenocarcinomas.
Esposito V, Baldi C, Zeppa P, Festa M, Guerriero L, d'Avenia M, Chetta M, Zullo F, De Laurenzi V, Turco MC, Rosati A, Guida M. Esposito V, et al. Among authors: de laurenzi v. J Cell Physiol. 2017 Feb;232(2):309-311. doi: 10.1002/jcp.25489. Epub 2016 Jul 22. J Cell Physiol. 2017. PMID: 27414463
Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8+ T cell number and tumour growth in pancreatic cancer.
Iorio V, Rosati A, D'Auria R, De Marco M, Marzullo L, Basile A, Festa M, Pascale M, Remondelli P, Capunzo M, Sala G, Damiani V, Amodio G, Di Nicola M, Lattanzio R, Turco MC, De Laurenzi V. Iorio V, et al. Among authors: de marco m, de laurenzi v. Gut. 2018 Apr;67(4):780-782. doi: 10.1136/gutjnl-2017-314225. Epub 2017 Aug 11. Gut. 2018. PMID: 28801350 Free PMC article. No abstract available.
Role of BAG3 in cancer progression: A therapeutic opportunity.
De Marco M, Basile A, Iorio V, Festa M, Falco A, Ranieri B, Pascale M, Sala G, Remondelli P, Capunzo M, Firpo MA, Pezzilli R, Marzullo L, Cavallo P, De Laurenzi V, Turco MC, Rosati A. De Marco M, et al. Among authors: de laurenzi v. Semin Cell Dev Biol. 2018 Jun;78:85-92. doi: 10.1016/j.semcdb.2017.08.049. Epub 2017 Aug 31. Semin Cell Dev Biol. 2018. PMID: 28864347 Review.
BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration.
Dufrusine B, Damiani V, Capone E, Pieragostino D, Dainese E, De Marco M, Reppucci F, Turco MC, Rosati A, Marzullo L, Sala G, Sallese M, De Laurenzi V. Dufrusine B, et al. Among authors: de marco m, de laurenzi v. J Cell Biochem. 2022 Jan;123(1):65-76. doi: 10.1002/jcb.30172. Epub 2021 Nov 6. J Cell Biochem. 2022. PMID: 34741485 Free PMC article.
Role of BAG3 protein in leukemia cell survival and response to therapy.
Rosati A, Basile A, Falco A, d'Avenia M, Festa M, Graziano V, De Laurenzi V, Arra C, Pascale M, Turco MC. Rosati A, et al. Among authors: de laurenzi v. Biochim Biophys Acta. 2012 Dec;1826(2):365-9. doi: 10.1016/j.bbcan.2012.06.001. Epub 2012 Jun 15. Biochim Biophys Acta. 2012. PMID: 22710027 Review.
The prosurvival protein BAG3: a new participant in vascular homeostasis.
Carrizzo A, Damato A, Ambrosio M, Falco A, Rosati A, Capunzo M, Madonna M, Turco MC, Januzzi JL, De Laurenzi V, Vecchione C. Carrizzo A, et al. Among authors: de laurenzi v. Cell Death Dis. 2016 Oct 20;7(10):e2431. doi: 10.1038/cddis.2016.321. Cell Death Dis. 2016. PMID: 27763645 Free PMC article.
153 results