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High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors.
Falvo E, Damiani V, Conti G, Boschi F, Messana K, Giacomini P, Milella M, De Laurenzi V, Morea V, Sala G, Fracasso G, Ceci P. Falvo E, et al. Among authors: de laurenzi v. J Exp Clin Cancer Res. 2021 Feb 10;40(1):63. doi: 10.1186/s13046-021-01851-8. J Exp Clin Cancer Res. 2021. PMID: 33568214 Free PMC article.
Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer.
Basile A, De Marco M, Festa M, Falco A, Iorio V, Guerriero L, Eletto D, Rea D, Arra C, Lamolinara A, Ballerini P, Damiani V, Rosati A, Sala G, Turco MC, Marzullo L, De Laurenzi V. Basile A, et al. Among authors: de marco m, de laurenzi v. Mol Oncol. 2019 Jun;13(6):1388-1399. doi: 10.1002/1878-0261.12492. Epub 2019 May 17. Mol Oncol. 2019. PMID: 30973679 Free PMC article.
ABCC3 is a novel target for the treatment of pancreatic cancer.
Adamska A, Ferro R, Lattanzio R, Capone E, Domenichini A, Damiani V, Chiorino G, Akkaya BG, Linton KJ, De Laurenzi V, Sala G, Falasca M. Adamska A, et al. Among authors: de laurenzi v. Adv Biol Regul. 2019 Aug;73:100634. doi: 10.1016/j.jbior.2019.04.004. Epub 2019 Apr 24. Adv Biol Regul. 2019. PMID: 31053501
Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer.
Adamska A, Domenichini A, Capone E, Damiani V, Akkaya BG, Linton KJ, Di Sebastiano P, Chen X, Keeton AB, Ramirez-Alcantara V, Maxuitenko Y, Piazza GA, De Laurenzi V, Sala G, Falasca M. Adamska A, et al. Among authors: de laurenzi v. J Exp Clin Cancer Res. 2019 Aug 5;38(1):312. doi: 10.1186/s13046-019-1308-7. J Exp Clin Cancer Res. 2019. PMID: 31378204 Free PMC article.
Secreted Gal-3BP is a novel promising target for non-internalizing Antibody-Drug Conjugates.
Giansanti F, Capone E, Ponziani S, Piccolo E, Gentile R, Lamolinara A, Di Campli A, Sallese M, Iacobelli V, Cimini A, De Laurenzi V, Lattanzio R, Piantelli M, Ippoliti R, Sala G, Iacobelli S. Giansanti F, et al. Among authors: de laurenzi v. J Control Release. 2019 Jan 28;294:176-184. doi: 10.1016/j.jconrel.2018.12.018. Epub 2018 Dec 13. J Control Release. 2019. PMID: 30553852 Free article.
BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration.
Dufrusine B, Damiani V, Capone E, Pieragostino D, Dainese E, De Marco M, Reppucci F, Turco MC, Rosati A, Marzullo L, Sala G, Sallese M, De Laurenzi V. Dufrusine B, et al. Among authors: de marco m, de laurenzi v. J Cell Biochem. 2022 Jan;123(1):65-76. doi: 10.1002/jcb.30172. Epub 2021 Nov 6. J Cell Biochem. 2022. PMID: 34741485 Free PMC article.
Proteomic Analysis of Marinesco-Sjogren Syndrome Fibroblasts Indicates Pro-Survival Metabolic Adaptation to SIL1 Loss.
Potenza F, Cufaro MC, Di Biase L, Panella V, Di Campli A, Ruggieri AG, Dufrusine B, Restelli E, Pietrangelo L, Protasi F, Pieragostino D, De Laurenzi V, Federici L, Chiesa R, Sallese M. Potenza F, et al. Among authors: de laurenzi v. Int J Mol Sci. 2021 Nov 18;22(22):12449. doi: 10.3390/ijms222212449. Int J Mol Sci. 2021. PMID: 34830330 Free PMC article.
153 results