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Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis.
Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, Salter MW, De Koninck Y. Ferrini F, et al. Among authors: de koninck y. Nat Neurosci. 2013 Feb;16(2):183-92. doi: 10.1038/nn.3295. Epub 2013 Jan 6. Nat Neurosci. 2013. PMID: 23292683 Free PMC article.
Chloride extrusion enhancers as novel therapeutics for neurological diseases.
Gagnon M, Bergeron MJ, Lavertu G, Castonguay A, Tripathy S, Bonin RP, Perez-Sanchez J, Boudreau D, Wang B, Dumas L, Valade I, Bachand K, Jacob-Wagner M, Tardif C, Kianicka I, Isenring P, Attardo G, Coull JA, De Koninck Y. Gagnon M, et al. Among authors: de koninck y. Nat Med. 2013 Nov;19(11):1524-8. doi: 10.1038/nm.3356. Epub 2013 Oct 6. Nat Med. 2013. PMID: 24097188 Free PMC article.
Microglia disrupt mesolimbic reward circuitry in chronic pain.
Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Taylor AM, et al. Among authors: de koninck y. J Neurosci. 2015 Jun 3;35(22):8442-50. doi: 10.1523/JNEUROSCI.4036-14.2015. J Neurosci. 2015. PMID: 26041913 Free PMC article.
Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine.
Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Taylor AM, et al. Among authors: de koninck y. Neuropsychopharmacology. 2016 Mar;41(4):949-59. doi: 10.1038/npp.2015.221. Epub 2015 Jul 23. Neuropsychopharmacology. 2016. PMID: 26202104 Free PMC article.
175 results