De Jonghe S - Search Results

1

Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model.

Ispas G, Koul A, Verbeeck J, Sheehan J, Sanders-Beer B, Roymans D, Andries K, Rouan MC, De Jonghe S, Bonfanti JF, Vanstockem M, Simmen K, Verloes R. Ispas G, et al. Among authors: de jonghe s. PLoS One. 2015 May 26;10(5):e0126959. doi: 10.1371/journal.pone.0126959. eCollection 2015. PLoS One. 2015. PMID: 26010881 Free PMC article.

2

Hemorrhagic cardiomyopathy in male mice treated with an NNRTI: the role of vitamin K.

De Jonghe S, Verbeeck J, Vinken P, Lammens L, Starckx S, Lachau-Durand S, Bouche MP, Willems B, Coussement W. De Jonghe S, et al. Toxicol Pathol. 2008 Feb;36(2):321-9. doi: 10.1177/0192623307311404. Epub 2008 Mar 26. Toxicol Pathol. 2008. PMID: 18367644

3

Dose- and Time-dependency of the Toxicity and Pharmacokinetic Profiles of Bedaquiline and Its N-desmethyl Metabolite in Dogs.

Smyej I, De Jonghe S, Looszova A, Mannens G, Verhaeghe T, Thijssen S, Starckx S, Lampo A, Rouan MC. Smyej I, et al. Among authors: de jonghe s. Toxicol Pathol. 2017 Jul;45(5):663-675. doi: 10.1177/0192623317723085. Epub 2017 Aug 9. Toxicol Pathol. 2017. PMID: 28789609

4

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct.

Movita D, van de Garde MD, Biesta P, Kreefft K, Haagmans B, Zuniga E, Herschke F, De Jonghe S, Janssen HL, Gama L, Boonstra A, Vanwolleghem T. Movita D, et al. Among authors: de jonghe s. J Virol. 2015 May;89(9):4809-17. doi: 10.1128/JVI.03733-14. Epub 2015 Feb 11. J Virol. 2015. PMID: 25673700 Free PMC article.

5

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection.

van de Garde MD, Movita D, van der Heide M, Herschke F, De Jonghe S, Gama L, Boonstra A, Vanwolleghem T. van de Garde MD, et al. Among authors: de jonghe s. PLoS One. 2016 Nov 3;11(11):e0166094. doi: 10.1371/journal.pone.0166094. eCollection 2016. PLoS One. 2016. PMID: 27812182 Free PMC article.

6

Carcinogenicity in rats of the SGLT2 inhibitor canagliflozin.

De Jonghe S, Proctor J, Vinken P, Feyen B, Wynant I, Marien D, Geys H, Mamidi RN, Johnson MD. De Jonghe S, et al. Chem Biol Interact. 2014 Dec 5;224:1-12. doi: 10.1016/j.cbi.2014.09.018. Epub 2014 Oct 5. Chem Biol Interact. 2014. PMID: 25289773

7

Methods to evaluate and improve the injection site tolerability of intravenous formulations prior to first-in-human testing.

Eichenbaum G, Zhou J, De Smedt A, De Jonghe S, Looszova A, Arien T, Van Goethem F, Vervoort I, Shukla U, Lammens L. Eichenbaum G, et al. Among authors: de jonghe s, de smedt a. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):394-406. doi: 10.1016/j.vascn.2013.08.002. Epub 2013 Aug 8. J Pharmacol Toxicol Methods. 2013. PMID: 23933112

8

Carbohydrate malabsorption mechanism for tumor formation in rats treated with the SGLT2 inhibitor canagliflozin.

Mamidi RN, Proctor J, De Jonghe S, Feyen B, Moesen E, Vinken P, Ma JY, Bryant S, Snook S, Louden C, Lammens G, Ways K, Kelley MF, Johnson MD. Mamidi RN, et al. Among authors: de jonghe s. Chem Biol Interact. 2014 Sep 25;221:109-18. doi: 10.1016/j.cbi.2014.08.001. Epub 2014 Aug 14. Chem Biol Interact. 2014. PMID: 25130857

9

Bilateral Symmetrical Idiopathic Necrotizing Encephalopathy: A New Syndrome in Sprague-Dawley Rats.

De Jonghe S, Abbott D, Vinken P, Moesen E, Feyen B, Lammens L, Vynckier A, De Lahunta A. De Jonghe S, et al. Among authors: de lahunta a. Toxicol Pathol. 2015 Dec;43(8):1141-8. doi: 10.1177/0192623315604409. Epub 2015 Oct 27. Toxicol Pathol. 2015. PMID: 26511844

10

Renal tubular and adrenal medullary tumors in the 2-year rat study with canagliflozin confirmed to be secondary to carbohydrate (glucose) malabsorption in the 15-month mechanistic rat study.

De Jonghe S, Johnson MD, Mamidi RNVS, Vinken P, Feyen B, Lammens G, Proctor J. De Jonghe S, et al. Chem Biol Interact. 2017 Nov 1;277:85-90. doi: 10.1016/j.cbi.2017.09.008. Epub 2017 Sep 12. Chem Biol Interact. 2017. PMID: 28916336

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