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Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Among authors: de jager pl. Nat Med. 2020 May;26(5):769-780. doi: 10.1038/s41591-020-0815-6. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284590 Free PMC article.
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ. Corneveaux JJ, et al. Among authors: de jager pl. Hum Mol Genet. 2010 Aug 15;19(16):3295-301. doi: 10.1093/hmg/ddq221. Epub 2010 Jun 9. Hum Mol Genet. 2010. PMID: 20534741 Free PMC article.
Parkinson's disease: genetics and pathogenesis.
Shulman JM, De Jager PL, Feany MB. Shulman JM, et al. Among authors: de jager pl. Annu Rev Pathol. 2011;6:193-222. doi: 10.1146/annurev-pathol-011110-130242. Annu Rev Pathol. 2011. PMID: 21034221 Review.
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL. Chibnik LB, et al. Among authors: de jager pl. Ann Neurol. 2011 Mar;69(3):560-9. doi: 10.1002/ana.22277. Epub 2011 Mar 9. Ann Neurol. 2011. PMID: 21391232 Free PMC article.
568 results