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Hydroxycarbamide decreases sickle reticulocyte adhesion to resting endothelium by inhibiting endothelial lutheran/basal cell adhesion molecule (Lu/BCAM) through phosphodiesterase 4A activation.
Chaar V, Laurance S, Lapoumeroulie C, Cochet S, De Grandis M, Colin Y, Elion J, Le Van Kim C, El Nemer W. Chaar V, et al. Among authors: de grandis m. J Biol Chem. 2014 Apr 18;289(16):11512-11521. doi: 10.1074/jbc.M113.506121. Epub 2014 Mar 10. J Biol Chem. 2014. PMID: 24616094 Free PMC article.
Impact of hydroxycarbamide and interferon-α on red cell adhesion and membrane protein expression in polycythemia vera.
Brusson M, De Grandis M, Cochet S, Bigot S, Marin M, Leduc M, Guillonneau F, Mayeux P, Peyrard T, Chomienne C, Le Van Kim C, Cassinat B, Kiladjian JJ, El Nemer W. Brusson M, et al. Among authors: de grandis m. Haematologica. 2018 Jun;103(6):972-981. doi: 10.3324/haematol.2017.182303. Epub 2018 Mar 29. Haematologica. 2018. PMID: 29599206 Free PMC article.
JAM-C Identifies Src Family Kinase-Activated Leukemia-Initiating Cells and Predicts Poor Prognosis in Acute Myeloid Leukemia.
De Grandis M, Bardin F, Fauriat C, Zemmour C, El-Kaoutari A, Sergé A, Granjeaud S, Pouyet L, Montersino C, Chretien AS, Mozziconacci MJ, Castellano R, Bidaut G, Boher JM, Collette Y, Mancini SJC, Vey N, Aurrand-Lions M. De Grandis M, et al. Cancer Res. 2017 Dec 1;77(23):6627-6640. doi: 10.1158/0008-5472.CAN-17-1223. Epub 2017 Sep 28. Cancer Res. 2017. PMID: 28972073
29 results