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A Fe2+-dependent self-inhibited state influences the druggability of human collagen lysyl hydroxylase (LH/PLOD) enzymes.
Scietti L, Moroni E, Mattoteia D, Fumagalli M, De Marco M, Negro L, Chiapparino A, Serapian SA, De Giorgi F, Faravelli S, Colombo G, Forneris F. Scietti L, et al. Among authors: de marco m, de giorgi f. Front Mol Biosci. 2022 Aug 25;9:876352. doi: 10.3389/fmolb.2022.876352. eCollection 2022. Front Mol Biosci. 2022. PMID: 36090047 Free PMC article.
New mechanistic insights to PLOD1-mediated human vascular disease.
Koenig SN, Cavus O, Williams J, Bernier M, Tonniges J, Sucharski H, Dew T, Akel M, Baker P, Madiai F, De Giorgi F, Scietti L, Faravelli S, Forneris F, Mohler PJ, Bradley EA. Koenig SN, et al. Among authors: de giorgi f. Transl Res. 2022 Jan;239:1-17. doi: 10.1016/j.trsl.2021.08.002. Epub 2021 Aug 13. Transl Res. 2022. PMID: 34400365 Free PMC article.
Pathological findings associated with the updated European Society of Cardiology 2022 guidelines for preoperative cardiac testing: an observational cohort modelling study.
Stroda A, Mauermann E, Ionescu D, Szczeklik W, De Hert S, Filipovic M, Beck Schimmer B, Spadaro S, Matute P, Ganter MT, Ovezov A, Turhan SC, van Waes J, Lagarto F, Theodoraki K, Gupta A, Gillmann HJ, Guzzetti L, Kotfis K, Larmann J, Corneci D, Buggy DJ, Howell SJ, Lurati Buse G; MET-REPAIR investigators. Stroda A, et al. Br J Anaesth. 2024 Apr;132(4):675-684. doi: 10.1016/j.bja.2023.12.036. Epub 2024 Feb 9. Br J Anaesth. 2024. PMID: 38336516
108 results