De Geest B - Search Results

1

Challenges in neoantigen-directed therapeutics.

Lybaert L, Lefever S, Fant B, Smits E, De Geest B, Breckpot K, Dirix L, Feldman SA, van Criekinge W, Thielemans K, van der Burg SH, Ott PA, Bogaert C. Lybaert L, et al. Among authors: de geest b. Cancer Cell. 2023 Jan 9;41(1):15-40. doi: 10.1016/j.ccell.2022.10.013. Epub 2022 Nov 10. Cancer Cell. 2023. PMID: 36368320 Free article. Review.

2

Tumor-Selective Activation of Toll-Like Receptor 7/8 Agonist Nano-Immunomodulator Generates Safe Anti-Tumor Immune Responses upon Systemic Administration.

Hao Y, Li H, Ge X, Liu Y, Li X, Liu Y, Chen H, Zhang S, Zou J, Huang L, Zhao F, Kang D, De Geest BG, Zhang Z. Hao Y, et al. Angew Chem Int Ed Engl. 2022 Dec 23;61(52):e202214992. doi: 10.1002/anie.202214992. Epub 2022 Nov 24. Angew Chem Int Ed Engl. 2022. PMID: 36331428

3

Towards a Rational Design of Antibody-Recruiting Molecules through a Computational Microscopy View of their Interactions with the Target Antibody.

Uvyn A, Tonneaux C, Fossépré M, Ouvrier-Buffet A, De Geest BG, Surin M. Uvyn A, et al. Chemistry. 2023 May 26;29(30):e202300474. doi: 10.1002/chem.202300474. Epub 2023 Apr 19. Chemistry. 2023. PMID: 36862311

4

Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)-Lipids for mRNA Lipid Nanoparticle Formulation.

Golba B, Soete M, Zhong Z, Sanders N, Du Prez FE, Houck HA, De Geest BG. Golba B, et al. Among authors: de geest bg. Angew Chem Int Ed Engl. 2023 Jun 5;62(23):e202301102. doi: 10.1002/anie.202301102. Epub 2023 Apr 12. Angew Chem Int Ed Engl. 2023. PMID: 36896730

5

Lipid nanoparticle composition for adjuvant formulation modulates disease after influenza virus infection in quadrivalent influenza vaccine vaccinated mice.

Jangra S, Lamoot A, Singh G, Laghlali G, Chen Y, Ye T, García-Sastre A, De Geest BG, Schotsaert M. Jangra S, et al. Among authors: de geest bg. Front Immunol. 2024 Apr 22;15:1370564. doi: 10.3389/fimmu.2024.1370564. eCollection 2024. Front Immunol. 2024. PMID: 38711520 Free PMC article.

6

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment.

De Vlieghere E, Van de Vijver K, Blondeel E, Carpentier N, Ghobeira R, Pauwels J, Riemann S, Minsart M, Fieuws C, Mestach J, Baeyens A, De Geyter N, Debbaut C, Denys H, Descamps B, Claes K, Vral A, Van Dorpe J, Gevaert K, De Geest BG, Ceelen W, Van Vlierberghe S, De Wever O. De Vlieghere E, et al. Among authors: de geest bg. Biomater Res. 2023 Oct 18;27(1):104. doi: 10.1186/s40824-023-00441-3. Biomater Res. 2023. PMID: 37853495 Free PMC article.

7

LXR signaling controls homeostatic dendritic cell maturation.

Bosteels V, Maréchal S, De Nolf C, Rennen S, Maelfait J, Tavernier SJ, Vetters J, Van De Velde E, Fayazpour F, Deswarte K, Lamoot A, Van Duyse J, Martens L, Bosteels C, Roelandt R, Emmaneel A, Van Gassen S, Boon L, Van Isterdael G, Guillas I, Vandamme N, Höglinger D, De Geest BG, Le Goff W, Saeys Y, Ravichandran KS, Lambrecht BN, Janssens S. Bosteels V, et al. Sci Immunol. 2023 May 12;8(83):eadd3955. doi: 10.1126/sciimmunol.add3955. Epub 2023 May 12. Sci Immunol. 2023. PMID: 37172103

8

Influenza breakthrough infection in vaccinated mice is characterized by non-pathological lung eosinophilia.

Chang LA, Choi A, Rathnasinghe R, Warang P, Noureddine M, Jangra S, Chen Y, De Geest BG, Schotsaert M. Chang LA, et al. Among authors: de geest bg. Front Immunol. 2023 Aug 4;14:1217181. doi: 10.3389/fimmu.2023.1217181. eCollection 2023. Front Immunol. 2023. PMID: 37600776 Free PMC article.

9

Thermally Triggered Triazolinedione-Tyrosine Bioconjugation with Improved Chemo- and Site-Selectivity.

Denijs E, Unal K, Bevernaege K, Kasmi S, De Geest BG, Winne JM. Denijs E, et al. Among authors: de geest bg. J Am Chem Soc. 2024 May 8;146(18):12672-12680. doi: 10.1021/jacs.4c02173. Epub 2024 Apr 29. J Am Chem Soc. 2024. PMID: 38683141

10

Thermosensitive polymer prodrug nanoparticles prepared by an all-aqueous nanoprecipitation process and application to combination therapy.

Guerassimoff L, Ferrere M, Van Herck S, Dehissi S, Nicolas V, De Geest BG, Nicolas J. Guerassimoff L, et al. Among authors: de geest bg. J Control Release. 2024 Apr 3;369:376-393. doi: 10.1016/j.jconrel.2024.03.049. Online ahead of print. J Control Release. 2024. PMID: 38554772 Free article.

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