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Generation and testing of engineered multimeric Fabs of trastuzumab.
Selis F, Sandomenico A, Cantile M, Sanna R, Calvanese L, Falcigno L, Dell'Omo P, Esperti A, De Falco S, Focà A, Caporale A, Iaccarino E, Truppo E, Scaramuzza S, Tonon G, Ruvo M. Selis F, et al. Among authors: de falco s. Int J Biol Macromol. 2020 Dec 1;164:4516-4531. doi: 10.1016/j.ijbiomac.2020.09.050. Epub 2020 Sep 14. Int J Biol Macromol. 2020. PMID: 32941911
Chemical synthesis of mouse cripto CFC variants.
Marasco D, Saporito A, Ponticelli S, Chambery A, De Falco S, Pedone C, Minchiotti G, Ruvo M. Marasco D, et al. Among authors: de falco s. Proteins. 2006 Aug 15;64(3):779-88. doi: 10.1002/prot.21043. Proteins. 2006. PMID: 16752415
Powerful anti-tumor and anti-angiogenic activity of a new anti-vascular endothelial growth factor receptor 1 peptide in colorectal cancer models.
Cicatiello V, Apicella I, Tudisco L, Tarallo V, Formisano L, Sandomenico A, Kim Y, Bastos-Carvalho A, Orlandi A, Ambati J, Ruvo M, Bianco R, De Falco S. Cicatiello V, et al. Among authors: de falco s. Oncotarget. 2015 Apr 30;6(12):10563-76. doi: 10.18632/oncotarget.3384. Oncotarget. 2015. PMID: 25868854 Free PMC article.
Human IgG1 antibodies suppress angiogenesis in a target-independent manner.
Bogdanovich S, Kim Y, Mizutani T, Yasuma R, Tudisco L, Cicatiello V, Bastos-Carvalho A, Kerur N, Hirano Y, Baffi JZ, Tarallo V, Li S, Yasuma T, Arpitha P, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ruvo M, Sandomenico A, Nozaki M, Ijima R, Kaneko H, Ogura Y, Terasaki H, Ambati BK, Leusen JH, Langdon WY, Clark MR, Armour KL, Bruhns P, Verbeek JS, Gelfand BD, De Falco S, Ambati J. Bogdanovich S, et al. Among authors: de falco s. Signal Transduct Target Ther. 2016;1:15001-. doi: 10.1038/sigtrans.2015.1. Epub 2016 Jan 28. Signal Transduct Target Ther. 2016. PMID: 26918197 Free PMC article.
Synthetic Peptide Libraries: From Random Mixtures to In Vivo Testing.
Sandomenico A, Caporale A, Doti N, Cross S, Cruciani G, Chambery A, De Falco S, Ruvo M. Sandomenico A, et al. Among authors: de falco s. Curr Med Chem. 2020;27(6):997-1016. doi: 10.2174/0929867325666180716110833. Curr Med Chem. 2020. PMID: 30009695
Recombinant humanized Fab fragments targeting the CFC domain of human Cripto-1.
Sandomenico A, Selis F, Sivaccumar JP, Olimpieri P, Iaccarino E, Cicatiello V, Cantile M, Sanna R, Leonardi A, De Falco S, Ruvo M. Sandomenico A, et al. Among authors: de falco s. Biochem Biophys Res Commun. 2024 Jan 29;694:149417. doi: 10.1016/j.bbrc.2023.149417. Epub 2023 Dec 21. Biochem Biophys Res Commun. 2024. PMID: 38150919
121 results