De Clercq E - Search Results

1

Design, synthesis and bioevaluation of novel maleamic amino acid ester conjugates of 3,5-bisarylmethylene-4-piperidones as cytostatic agents.

Youssef D, Potter E, Jha M, De Clercq E, Balzarini J, Stables JP, Jha A. Youssef D, et al. Among authors: de clercq e. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6364-7. doi: 10.1016/j.bmcl.2009.09.069. Epub 2009 Sep 22. Bioorg Med Chem Lett. 2009. PMID: 19819135

2

A mercapto analogue of 5'-noraristeromycin.

Das SR, Schneller SW, Balzarini J, De Clercq E. Das SR, et al. Among authors: de clercq e. Bioorg Med Chem. 2002 Feb;10(2):457-60. doi: 10.1016/s0968-0896(01)00271-1. Bioorg Med Chem. 2002. PMID: 11741794

3

Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.

Liekens S, Bilsen F, De Clercq E, Priego EM, Camarasa MJ, Pérez-Pérez MJ, Balzarini J. Liekens S, et al. Among authors: de clercq e. FEBS Lett. 2002 Jan 2;510(1-2):83-8. doi: 10.1016/s0014-5793(01)03233-1. FEBS Lett. 2002. PMID: 11755536 Free article.

4

Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus.

Mavel S, Renou JL, Galtier C, Allouchi H, Snoeck R, Andrei G, De Clercq E, Balzarini J, Gueiffier A. Mavel S, et al. Among authors: de clercq e. Bioorg Med Chem. 2002 Apr;10(4):941-6. doi: 10.1016/s0968-0896(01)00347-9. Bioorg Med Chem. 2002. PMID: 11836102

5

Cytotoxic 1,4-bis(2-oxo-1-cycloalkylmethylene)benzenes and related compounds.

Dimmock JR, Jha A, Kumar P, Zello GA, Quail JW, Oloo EO, Oucharek JJ, Pasha MK, Seitz D, Sharma RK, Allen TM, Santos CL, Manavathu EK, De Clercq E, Balzarini J, Stables JP. Dimmock JR, et al. Among authors: de clercq e. Eur J Med Chem. 2002 Jan;37(1):35-44. doi: 10.1016/s0223-5234(01)01294-6. Eur J Med Chem. 2002. PMID: 11841873

6

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.

Holý A, Votruba I, Masojídková M, Andrei G, Snoeck R, Naesens L, De Clercq E, Balzarini J. Holý A, et al. Among authors: de clercq e. J Med Chem. 2002 Apr 25;45(9):1918-29. doi: 10.1021/jm011095y. J Med Chem. 2002. PMID: 11960502

7

Synthesis and in vitro cytotoxic and antiviral activities of 1-(2,5,6-trideoxy-6-halogenohept-5-enofuranurononitrile)thymine and derivatives.

Tronchet JM, Chalard F, Rivara-Minten E, Seman M, De Clercq E, Balzarini J, Dilda P. Tronchet JM, et al. Among authors: de clercq e. Nucleosides Nucleotides Nucleic Acids. 2002;21(3):191-206. doi: 10.1081/ncn-120003285. Nucleosides Nucleotides Nucleic Acids. 2002. PMID: 11991161

8

Synthesis, antiviral and cytostatic activities, of carbocyclic nucleosides incorporating a modified cyclopentane ring. IV. Adenosine and uridine analogues.

Nieto MI, Caamaño O, Fernández F, Gómez M, Balzarini J, De Clercq E. Nieto MI, et al. Among authors: de clercq e. Nucleosides Nucleotides Nucleic Acids. 2002;21(3):243-55. doi: 10.1081/NCN-120003289. Nucleosides Nucleotides Nucleic Acids. 2002. PMID: 11991165

9

Synthesis and biological evaluation of isonucleosides derived from methyl 3,5-anhydro-2-O-(2-fluorobenzyl)-D-xylofuranosides.

Wirsching J, Schulze O, Voss J, Giesler A, Kopf J, Adiwidjaja G, Balzarini J, De Clercq E. Wirsching J, et al. Among authors: de clercq e. Nucleosides Nucleotides Nucleic Acids. 2002;21(3):257-74. doi: 10.1081/ncn-120003290. Nucleosides Nucleotides Nucleic Acids. 2002. PMID: 11991166

10

The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase.

Balzarini J, Liekens S, Esnouf R, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochemistry. 2002 May 21;41(20):6517-24. doi: 10.1021/bi0255930. Biochemistry. 2002. PMID: 12009916

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