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Molecular Actions of PPARα in Lipid Metabolism and Inflammation.
Bougarne N, Weyers B, Desmet SJ, Deckers J, Ray DW, Staels B, De Bosscher K. Bougarne N, et al. Among authors: de bosscher k. Endocr Rev. 2018 Oct 1;39(5):760-802. doi: 10.1210/er.2018-00064. Endocr Rev. 2018. PMID: 30020428 Free article. Review.
Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.
Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B. Delerive P, et al. Among authors: de bosscher k. J Biol Chem. 1999 Nov 5;274(45):32048-54. doi: 10.1074/jbc.274.45.32048. J Biol Chem. 1999. PMID: 10542237 Free article.
A paradigm for gene regulation: inflammation, NF-kappaB and PPAR.
Vanden Berghe W, Vermeulen L, Delerive P, De Bosscher K, Staels B, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. Adv Exp Med Biol. 2003;544:181-96. doi: 10.1007/978-1-4419-9072-3_22. Adv Exp Med Biol. 2003. PMID: 14713228 Review.
A fully dissociated compound of plant origin for inflammatory gene repression.
De Bosscher K, Vanden Berghe W, Beck IM, Van Molle W, Hennuyer N, Hapgood J, Libert C, Staels B, Louw A, Haegeman G. De Bosscher K, et al. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15827-32. doi: 10.1073/pnas.0505554102. Epub 2005 Oct 21. Proc Natl Acad Sci U S A. 2005. PMID: 16243974 Free PMC article.
PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K. Bougarne N, et al. Among authors: de bosscher k. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7397-402. doi: 10.1073/pnas.0806742106. Epub 2009 Apr 17. Proc Natl Acad Sci U S A. 2009. PMID: 19376972 Free PMC article.
130 results