De Bosscher K - Search Results

1

Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads.

Chirumamilla CS, Palagani A, Kamaraj B, Declerck K, Verbeek MWC, Oksana R, De Bosscher K, Bougarne N, Ruttens B, Gevaert K, Houtman R, De Vos WH, Joossens J, Van Der Veken P, Augustyns K, Van Ostade X, Bogaerts A, De Winter H, Vanden Berghe W. Chirumamilla CS, et al. Among authors: de vos wh, de winter h, de bosscher k. Front Immunol. 2017 Nov 1;8:1324. doi: 10.3389/fimmu.2017.01324. eCollection 2017. Front Immunol. 2017. PMID: 29163463 Free PMC article.

2

Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation.

De Bosscher K, Schmitz ML, Vanden Berghe W, Plaisance S, Fiers W, Haegeman G. De Bosscher K, et al. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13504-9. doi: 10.1073/pnas.94.25.13504. Proc Natl Acad Sci U S A. 1997. PMID: 9391055 Free PMC article.

3

p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor.

Vanden Berghe W, Plaisance S, Boone E, De Bosscher K, Schmitz ML, Fiers W, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. J Biol Chem. 1998 Feb 6;273(6):3285-90. doi: 10.1074/jbc.273.6.3285. J Biol Chem. 1998. PMID: 9452444 Free article.

4

Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kappaB-dependent mechanism.

Vanden Berghe W, Francesconi E, De Bosscher K, Resche-Rigon M, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. Mol Pharmacol. 1999 Oct;56(4):797-806. Mol Pharmacol. 1999. PMID: 10496964

5

The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

Vanden Berghe W, De Bosscher K, Boone E, Plaisance S, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k. J Biol Chem. 1999 Nov 5;274(45):32091-8. doi: 10.1074/jbc.274.45.32091. J Biol Chem. 1999. PMID: 10542243 Free article.

6

Glucocorticoids repress NF-kappaB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell.

De Bosscher K, Vanden Berghe W, Vermeulen L, Plaisance S, Boone E, Haegeman G. De Bosscher K, et al. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):3919-24. doi: 10.1073/pnas.97.8.3919. Proc Natl Acad Sci U S A. 2000. PMID: 10760263 Free PMC article.

7

Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: negative interference of activated glucocorticoid receptor with transcription factors.

De Bosscher K, Vanden Berghe W, Haegeman G. De Bosscher K, et al. J Neuroimmunol. 2000 Sep 1;109(1):16-22. doi: 10.1016/s0165-5728(00)00297-6. J Neuroimmunol. 2000. PMID: 10969176 Review.

8

Signal transduction by tumor necrosis factor and gene regulation of the inflammatory cytokine interleukin-6.

Vanden Berghe W, Vermeulen L, De Wilde G, De Bosscher K, Boone E, Haegeman G. Vanden Berghe W, et al. Among authors: de bosscher k, de wilde g. Biochem Pharmacol. 2000 Oct 15;60(8):1185-95. doi: 10.1016/s0006-2952(00)00412-3. Biochem Pharmacol. 2000. PMID: 11007957 Review.

9

Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators.

De Bosscher K, Vanden Berghe W, Haegeman G. De Bosscher K, et al. Mol Endocrinol. 2001 Feb;15(2):219-27. doi: 10.1210/mend.15.2.0591. Mol Endocrinol. 2001. PMID: 11158329

10

The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression.

De Bosscher K, Vanden Berghe W, Haegeman G. De Bosscher K, et al. Endocr Rev. 2003 Aug;24(4):488-522. doi: 10.1210/er.2002-0006. Endocr Rev. 2003. PMID: 12920152 Review.

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