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Fatty acid carbon is essential for dNTP synthesis in endothelial cells.
Schoors S, Bruning U, Missiaen R, Queiroz KC, Borgers G, Elia I, Zecchin A, Cantelmo AR, Christen S, Goveia J, Heggermont W, Goddé L, Vinckier S, Van Veldhoven PP, Eelen G, Schoonjans L, Gerhardt H, Dewerchin M, Baes M, De Bock K, Ghesquière B, Lunt SY, Fendt SM, Carmeliet P. Schoors S, et al. Among authors: de bock k. Nature. 2015 Apr 9;520(7546):192-197. doi: 10.1038/nature14362. Epub 2015 Apr 1. Nature. 2015. PMID: 25830893 Free PMC article.
Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis.
Kalucka J, Bierhansl L, Conchinha NV, Missiaen R, Elia I, Brüning U, Scheinok S, Treps L, Cantelmo AR, Dubois C, de Zeeuw P, Goveia J, Zecchin A, Taverna F, Morales-Rodriguez F, Brajic A, Conradi LC, Schoors S, Harjes U, Vriens K, Pilz GA, Chen R, Cubbon R, Thienpont B, Cruys B, Wong BW, Ghesquière B, Dewerchin M, De Bock K, Sagaert X, Jessberger S, Jones EAV, Gallez B, Lambrechts D, Mazzone M, Eelen G, Li X, Fendt SM, Carmeliet P. Kalucka J, et al. Among authors: de zeeuw p, de bock k. Cell Metab. 2018 Dec 4;28(6):881-894.e13. doi: 10.1016/j.cmet.2018.07.016. Epub 2018 Aug 23. Cell Metab. 2018. PMID: 30146488 Free article.
Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis.
Broadfield LA, Duarte JAG, Schmieder R, Broekaert D, Veys K, Planque M, Vriens K, Karasawa Y, Napolitano F, Fujita S, Fujii M, Eto M, Holvoet B, Vangoitsenhoven R, Fernandez-Garcia J, Van Elsen J, Dehairs J, Zeng J, Dooley J, Rubio RA, van Pelt J, Grünewald TGP, Liston A, Mathieu C, Deroose CM, Swinnen JV, Lambrechts D, di Bernardo D, Kuroda S, De Bock K, Fendt SM. Broadfield LA, et al. Among authors: de bock k. Cancer Res. 2021 Apr 15;81(8):1988-2001. doi: 10.1158/0008-5472.CAN-20-1954. Epub 2021 Mar 9. Cancer Res. 2021. PMID: 33687947 Free PMC article.
Role of Mitochondrial Complex IV in Age-Dependent Obesity.
Soro-Arnaiz I, Li QOY, Torres-Capelli M, Meléndez-Rodríguez F, Veiga S, Veys K, Sebastian D, Elorza A, Tello D, Hernansanz-Agustín P, Cogliati S, Moreno-Navarrete JM, Balsa E, Fuertes E, Romanos E, Martínez-Ruiz A, Enriquez JA, Fernandez-Real JM, Zorzano A, De Bock K, Aragonés J. Soro-Arnaiz I, et al. Among authors: de bock k. Cell Rep. 2016 Sep 13;16(11):2991-3002. doi: 10.1016/j.celrep.2016.08.041. Cell Rep. 2016. PMID: 27626667 Free article.
Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization.
Zhang J, Muri J, Fitzgerald G, Gorski T, Gianni-Barrera R, Masschelein E, D'Hulst G, Gilardoni P, Turiel G, Fan Z, Wang T, Planque M, Carmeliet P, Pellerin L, Wolfrum C, Fendt SM, Banfi A, Stockmann C, Soro-Arnáiz I, Kopf M, De Bock K. Zhang J, et al. Among authors: de bock k. Cell Metab. 2020 Jun 2;31(6):1136-1153.e7. doi: 10.1016/j.cmet.2020.05.004. Cell Metab. 2020. PMID: 32492393 Free PMC article.
Endothelial Cell Metabolism in Health and Disease.
Rohlenova K, Veys K, Miranda-Santos I, De Bock K, Carmeliet P. Rohlenova K, et al. Among authors: de bock k. Trends Cell Biol. 2018 Mar;28(3):224-236. doi: 10.1016/j.tcb.2017.10.010. Epub 2017 Nov 16. Trends Cell Biol. 2018. PMID: 29153487 Review.
87 results