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Individuals with obesity who survive SARS-CoV-2 infection have preserved antigen-specific T cell frequencies.
Obesity (Silver Spring). 2022 Oct;30(10):1927-1931. doi: 10.1002/oby.23526. Epub 2022 Sep 1.
Obesity (Silver Spring). 2022.
PMID: 35766325
Free PMC article.
Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity.
Kedia-Mehta N, Tobin L, Zaiatz-Bittencourt V, Pisarska MM, De Barra C, Choi C, Elamin E, O'Shea D, Gardiner CM, Finlay DK, Hogan AE.
Kedia-Mehta N, et al. Among authors: de barra c.
Blood Adv. 2021 Nov 9;5(21):4447-4455. doi: 10.1182/bloodadvances.2021005047.
Blood Adv. 2021.
PMID: 34607345
Free PMC article.
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Iron Is Critical for Mucosal-Associated Invariant T Cell Metabolism and Effector Functions.
Ryan EK, Clutter C, De Barra C, Jenkins BJ, O'Shaughnessy S, Ryan OK, McKenna C, Heneghan HM, Walsh F, Finlay DK, Sinclair LV, Jones N, Leung DT, O'Shea D, Hogan AE.
Ryan EK, et al. Among authors: de barra c.
J Immunol. 2024 Jun 1;212(11):1706-1713. doi: 10.4049/jimmunol.2300649.
J Immunol. 2024.
PMID: 38619286
Free PMC article.
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NK cells vs. obesity: A tale of dysfunction & redemption.
De Barra C, O'Shea D, Hogan AE.
De Barra C, et al.
Clin Immunol. 2023 Oct;255:109744. doi: 10.1016/j.clim.2023.109744. Epub 2023 Aug 19.
Clin Immunol. 2023.
PMID: 37604354
Free article.
Review.
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Glucagon-like peptide-1 therapy in people with obesity restores natural killer cell metabolism and effector function.
De Barra C, Khalil M, Mat A, O'Donnell C, Shaamile F, Brennan K, O'Shea D, Hogan AE.
De Barra C, et al.
Obesity (Silver Spring). 2023 Jul;31(7):1787-1797. doi: 10.1002/oby.23772. Epub 2023 May 9.
Obesity (Silver Spring). 2023.
PMID: 37157931
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The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis.
Kedia-Mehta N, Pisarska MM, Rollings C, O'Neill C, De Barra C, Foley C, Wood NAW, Wrigley-Kelly N, Veerapen N, Besra G, Bergin R, Jones N, O'Shea D, Sinclair LV, Hogan AE.
Kedia-Mehta N, et al. Among authors: de barra c.
Sci Signal. 2023 Apr 18;16(781):eabo2709. doi: 10.1126/scisignal.abo2709. Epub 2023 Apr 18.
Sci Signal. 2023.
PMID: 37071733
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Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu.
Gallagher C, Mahon JM, O'Neill C, Cassidy FC, Dunbar H, De Barra C, Cadden C, Pisarska MM, Wood NAW, Masterson JC, McNamee EN, Schrumpf E, English K, O'Shea D, Tobin AM, Hogan AE.
Gallagher C, et al. Among authors: de barra c.
J Invest Dermatol. 2023 Jun;143(6):1094-1097.e2. doi: 10.1016/j.jid.2022.11.011. Epub 2022 Dec 11.
J Invest Dermatol. 2023.
PMID: 36516909
No abstract available.
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Antigen specific T cells in people with obesity at five months following ChAdOx1 COVID-19 vaccination.
Kelly NEW, De Barra C, Shaamile F, Holland A, Shaw L, Mallon PWG, O'Connell J, Hogan AE, O'Shea D.
Kelly NEW, et al. Among authors: de barra c.
Int J Obes (Lond). 2023 Jan;47(1):83-86. doi: 10.1038/s41366-022-01235-8. Epub 2022 Nov 8.
Int J Obes (Lond). 2023.
PMID: 36347936
Free PMC article.
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