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ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.
Hsieh RC, Krishnan S, Wu RC, Boda AR, Liu A, Winkler M, Hsu WH, Lin SH, Hung MC, Chan LC, Bhanu KR, Srinivasamani A, De Azevedo RA, Chou YC, DePinho RA, Gubin M, Vilar E, Chen CH, Slay R, Jayaprakash P, Hegde SM, Hartley G, Lea ST, Prasad R, Morrow B, Couillault CA, Steiner M, Wang CC, Venkatesulu BP, Taniguchi C, Kim YSB, Chen J, Rudqvist NP, Curran MA. Hsieh RC, et al. Among authors: de azevedo ra. Sci Immunol. 2022 Jun 10;7(72):eabl9330. doi: 10.1126/sciimmunol.abl9330. Epub 2022 Jun 10. Sci Immunol. 2022. PMID: 35687697 Free PMC article.
Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.
de Azevedo RA, Figueiredo CR, Ferreira AK, Matsuo AL, Massaoka MH, Girola N, Auada AV, Farias CF, Pasqualoto KF, Rodrigues CP, Barbuto JA, Levy D, Bydlowski SP, de Sá-Junior PL, Travassos LR, Lebrun I. de Azevedo RA, et al. Among authors: de sa junior pl. Peptides. 2015 Jun;68:113-9. doi: 10.1016/j.peptides.2014.09.024. Epub 2014 Oct 14. Peptides. 2015. PMID: 25305549
Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells.
da Cunha FFM, Mugnol KCU, de Melo FM, Nascimento MVSQ, de Azevedo RA, Santos RTS, Magalhães JA, Miguel DC, Tada DB, Mortara RA, Travassos LR, Arruda DC. da Cunha FFM, et al. Among authors: de melo fm, de azevedo ra. Anticancer Agents Med Chem. 2019;19(3):389-401. doi: 10.2174/1871520618666181109164246. Anticancer Agents Med Chem. 2019. PMID: 30417795
Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network.
Ferreira AK, de-Sá-Júnior PL, Pasqualoto KF, de Azevedo RA, Câmara DA, Costa AS, Figueiredo CR, Matsuo AL, Massaoka MH, Auada AV, Lebrun I, Damião MC, Tavares MT, Magri FM, Kerkis I, Parise Filho R. Ferreira AK, et al. Among authors: de sa junior pl, de azevedo ra. Biochimie. 2014 Apr;99:195-207. doi: 10.1016/j.biochi.2013.12.008. Epub 2013 Dec 16. Biochimie. 2014. PMID: 24355203
Edelfosine: An Antitumor Drug Prototype.
Teixeira SF, Rodrigues CP, Costa CJS, Pettinati TN, de Azevedo RA, Mambelli LI, Jorge SD, Ramos RN, Ferro ES, Barbuto JAM, Ferreira AK. Teixeira SF, et al. Among authors: de azevedo ra. Anticancer Agents Med Chem. 2018;18(6):865-874. doi: 10.2174/1871520618666180105165431. Anticancer Agents Med Chem. 2018. PMID: 29308743
RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model.
Ferreira AK, Tavares MT, Pasqualoto KF, de Azevedo RA, Teixeira SF, Ferreira-Junior WA, Bertin AM, de-Sá-Junior PL, Barbuto JA, Figueiredo CR, Cury Y, Damião MC, Parise-Filho R. Ferreira AK, et al. Among authors: de sa junior pl, de azevedo ra. Tumour Biol. 2015 Sep;36(9):7251-67. doi: 10.1007/s13277-015-3441-z. Epub 2015 Apr 20. Tumour Biol. 2015. PMID: 25894379
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.
de-Sá-Júnior PL, Pasqualoto KF, Ferreira AK, Tavares MT, Damião MC, de Azevedo RA, Câmara DA, Pereira A, de Souza DM, Parise Filho R. de-Sá-Júnior PL, et al. Among authors: de azevedo ra, de souza dm. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):385-98. doi: 10.1016/j.taap.2012.11.029. Epub 2012 Dec 10. Toxicol Appl Pharmacol. 2013. PMID: 23238560
37 results