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Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma.
Zhou Q, Phoa AF, Abbassi RH, Hoque M, Reekie TA, Font JS, Ryan RM, Stringer BW, Day BW, Johns TG, Munoz L, Kassiou M. Zhou Q, et al. Among authors: day bw. J Med Chem. 2017 Mar 9;60(5):2052-2070. doi: 10.1021/acs.jmedchem.6b01840. Epub 2017 Feb 28. J Med Chem. 2017. PMID: 28206758
Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma.
Neubauer HA, Tea MN, Zebol JR, Gliddon BL, Stefanidis C, Moretti PAB, Pitman MR, Costabile M, Kular J, Stringer BW, Day BW, Samuel MS, Bonder CS, Powell JA, Pitson SM. Neubauer HA, et al. Among authors: day bw. Oncogene. 2019 Feb;38(8):1151-1165. doi: 10.1038/s41388-018-0504-9. Epub 2018 Sep 24. Oncogene. 2019. PMID: 30250299 Free PMC article.
MK2 Inhibition Induces p53-Dependent Senescence in Glioblastoma Cells.
Phoa AF, Recasens A, Gurgis FMS, Betts TA, Menezes SV, Chau D, Nordfors K, Haapasalo J, Haapasalo H, Johns TG, Stringer BW, Day BW, Buckland ME, Lalaoui N, Munoz L. Phoa AF, et al. Among authors: day bw. Cancers (Basel). 2020 Mar 11;12(3):654. doi: 10.3390/cancers12030654. Cancers (Basel). 2020. PMID: 32168910 Free PMC article.
Global phosphoproteomics reveals DYRK1A regulates CDK1 activity in glioblastoma cells.
Recasens A, Humphrey SJ, Ellis M, Hoque M, Abbassi RH, Chen B, Longworth M, Needham EJ, James DE, Johns TG, Day BW, Kassiou M, Yang P, Munoz L. Recasens A, et al. Among authors: day bw. Cell Death Discov. 2021 Apr 16;7(1):81. doi: 10.1038/s41420-021-00456-6. Cell Death Discov. 2021. PMID: 33863878 Free PMC article.
228 results