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Optimized chemical probes for REV-ERBα.
J Med Chem. 2013 Jun 13;56(11):4729-37. doi: 10.1021/jm400458q. Epub 2013 May 23.
J Med Chem. 2013.
PMID: 23656296
Free PMC article.
Identification and Optimization of Novel Small c-Abl Kinase Activators Using Fragment and HTS Methodologies.
Simpson GL, Bertrand SM, Borthwick JA, Campobasso N, Chabanet J, Chen S, Coggins J, Cottom J, Christensen SB, Dawson HC, Evans HL, Hobbs AN, Hong X, Mangatt B, Munoz-Muriedas J, Oliff A, Qin D, Scott-Stevens P, Ward P, Washio Y, Yang J, Young RJ.
Simpson GL, et al. Among authors: dawson hc.
J Med Chem. 2019 Feb 28;62(4):2154-2171. doi: 10.1021/acs.jmedchem.8b01872. Epub 2019 Feb 11.
J Med Chem. 2019.
PMID: 30689376
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Bis tertiary amide inhibitors of the HIV-1 protease generated via protein structure-based iterative design.
Melnick M, Reich SH, Lewis KK, Mitchell LJ Jr, Nguyen D, Trippe AJ, Dawson H, Davies JF 2nd, Appelt K, Wu BW, Musick L, Gehlhaar DK, Webber S, Shetty B, Kosa M, Kahil D, Andrada D.
Melnick M, et al.
J Med Chem. 1996 Jul 5;39(14):2795-811. doi: 10.1021/jm960092w.
J Med Chem. 1996.
PMID: 8709110
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(S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.
Cosford ND, Bleicher L, Herbaut A, McCallum JS, Vernier JM, Dawson H, Whitten JP, Adams P, Chavez-Noriega L, Correa LD, Crona JH, Mahaffy LS, Menzaghi F, Rao TS, Reid R, Sacaan AI, Santori E, Stauderman KA, Whelan K, Lloyd GK, McDonald IA.
Cosford ND, et al.
J Med Chem. 1996 Aug 16;39(17):3235-7. doi: 10.1021/jm960328w.
J Med Chem. 1996.
PMID: 8765504
No abstract available.
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Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.
Reich SH, Melnick M, Davies JF 2nd, Appelt K, Lewis KK, Fuhry MA, Pino M, Trippe AJ, Nguyen D, Dawson H, et al.
Reich SH, et al.
Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3298-302. doi: 10.1073/pnas.92.8.3298.
Proc Natl Acad Sci U S A. 1995.
PMID: 7724556
Free PMC article.
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