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143 results

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Page 1
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB. Brown AJH, et al. Among authors: dawson gr. Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001. Cell. 2021. PMID: 34822784 Free article. Clinical Trial.
Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypy.
Perini F, Nazimek JM, Mckie S, Capitão LP, Scaife J, Pal D, Browning M, Dawson GR, Nishikawa H, Campbell U, Hopkins SC, Loebel A, Elliott R, Harmer CJ, Deakin B, Koblan KS. Perini F, et al. Among authors: dawson gr. Schizophrenia (Heidelb). 2023 Aug 7;9(1):49. doi: 10.1038/s41537-023-00385-6. Schizophrenia (Heidelb). 2023. PMID: 37550314 Free PMC article.
A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies.
Post A, Smart TS, Krikke-Workel J, Dawson GR, Harmer CJ, Browning M, Jackson K, Kakar R, Mohs R, Statnick M, Wafford K, McCarthy A, Barth V, Witkin JM. Post A, et al. Among authors: dawson gr. Neuropsychopharmacology. 2016 Jun;41(7):1803-12. doi: 10.1038/npp.2015.348. Epub 2015 Nov 20. Neuropsychopharmacology. 2016. PMID: 26585287 Free PMC article. Clinical Trial.
The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial.
Kingslake J, Dias R, Dawson GR, Simon J, Goodwin GM, Harmer CJ, Morriss R, Brown S, Guo B, Dourish CT, Ruhé HG, Lever AG, Veltman DJ, van Schaik A, Deckert J, Reif A, Stäblein M, Menke A, Gorwood P, Voegeli G, Pérez V, Browning M. Kingslake J, et al. Among authors: dawson gr. Trials. 2017 Nov 23;18(1):558. doi: 10.1186/s13063-017-2247-2. Trials. 2017. PMID: 29169399 Free PMC article. Clinical Trial.
Relating constructs of attention and working memory to social withdrawal in Alzheimer's disease and schizophrenia: issues regarding paradigm selection.
Gilmour G, Porcelli S, Bertaina-Anglade V, Arce E, Dukart J, Hayen A, Lobo A, Lopez-Anton R, Merlo Pich E, Pemberton DJ, Havenith MN, Glennon JC, Harel BT, Dawson G, Marston H, Kozak R, Serretti A. Gilmour G, et al. Neurosci Biobehav Rev. 2019 Feb;97:47-69. doi: 10.1016/j.neubiorev.2018.09.025. Epub 2018 Nov 3. Neurosci Biobehav Rev. 2019. PMID: 30399355 Free article. Review.
When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial).
Brown S, Ploeger C, Guo B, Petersen JJ, Beckenstrom AC, Browning M, Dawson GR, Deckert J, Dias R, Dourish CT, Gorwood P, Kingslake J, Menke A, Sola VP, Reif A, Ruhe H, Simon J, Stäblein M, van Schaik A, Veltman DJ, Morriss R; PReDicT Group. Brown S, et al. Among authors: dawson gr. Compr Psychiatry. 2024 Jul;132:152467. doi: 10.1016/j.comppsych.2024.152467. Epub 2024 Mar 7. Compr Psychiatry. 2024. PMID: 38608615 Free article. Clinical Trial.
The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial.
Browning M, Bilderbeck AC, Dias R, Dourish CT, Kingslake J, Deckert J, Goodwin GM, Gorwood P, Guo B, Harmer CJ, Morriss R, Reif A, Ruhe HG, van Schaik A, Simon J, Sola VP, Veltman DJ, Elices M, Lever AG, Menke A, Scanferla E, Stäblein M, Dawson GR. Browning M, et al. Among authors: dawson gr. Neuropsychopharmacology. 2021 Jun;46(7):1307-1314. doi: 10.1038/s41386-021-00981-z. Epub 2021 Feb 26. Neuropsychopharmacology. 2021. PMID: 33637837 Free PMC article. Clinical Trial.
143 results