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A peptide-based vaccine for Mycobacterium avium subspecies paratuberculosis.
Abdellrazeq GS, Elnaggar MM, Bannantine JP, Schneider DA, Souza CD, Hwang J, Mahmoud AHA, Hulubei V, Fry LM, Park KT, Davis WC. Abdellrazeq GS, et al. Among authors: davis wc. Vaccine. 2019 May 9;37(21):2783-2790. doi: 10.1016/j.vaccine.2019.04.040. Epub 2019 Apr 16. Vaccine. 2019. PMID: 31003915
relA is Achilles' heel for mycobacterial pathogens as demonstrated with deletion mutants in Mycobacterium avium subsp. paratuberculosis and mycobacterium bovis bacillus Calmette-Guérin (BCG).
Abdellrazeq GS, Mahmoud AH, Park KT, Fry LM, Elnaggar MM, Schneider DA, Hulubei V, Davis WC. Abdellrazeq GS, et al. Among authors: davis wc. Tuberculosis (Edinb). 2020 Jan;120:101904. doi: 10.1016/j.tube.2020.101904. Epub 2020 Jan 15. Tuberculosis (Edinb). 2020. PMID: 32090858
A Mycobacterium avium subsp. paratuberculosis relA deletion mutant and a 35 kDa major membrane protein elicit development of cytotoxic T lymphocytes with ability to kill intracellular bacteria.
Abdellrazeq GS, Elnaggar MM, Bannantine JP, Park KT, Souza CD, Backer B, Hulubei V, Fry LM, Khaliel SA, Torky HA, Schneider DA, Davis WC. Abdellrazeq GS, et al. Among authors: davis wc. Vet Res. 2018 Jun 26;49(1):53. doi: 10.1186/s13567-018-0549-3. Vet Res. 2018. PMID: 29941017 Free PMC article.
Simultaneous cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine.
Abdellrazeq GS, Fry LM, Elnaggar MM, Bannantine JP, Schneider DA, Chamberlin WM, Mahmoud AHA, Park KT, Hulubei V, Davis WC. Abdellrazeq GS, et al. Among authors: davis wc. Vaccine. 2020 Feb 18;38(8):2016-2025. doi: 10.1016/j.vaccine.2019.12.052. Epub 2020 Jan 3. Vaccine. 2020. PMID: 31902643
531 results