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Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.
Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB. Preston S, et al. Among authors: davis ra. FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7. FASEB J. 2017. PMID: 28687609
Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold.
Schwartz BD, Skinner-Adams TS, Andrews KT, Coster MJ, Edstein MD, MacKenzie D, Charman SA, Koltun M, Blundell S, Campbell A, Pouwer RH, Quinn RJ, Beattie KD, Healy PC, Davis RA. Schwartz BD, et al. Among authors: davis ra. Org Biomol Chem. 2015 Feb 7;13(5):1558-70. doi: 10.1039/c4ob01849d. Org Biomol Chem. 2015. PMID: 25490858 Free article.
450 results