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APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, Kahn M, Blanco-Duque C, Lavoie N, Liu L, Reyes R, Lin YT, Ko T, R'Bibo L, Ralvenius WT, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: davila velderrain j. Nature. 2022 Nov;611(7937):769-779. doi: 10.1038/s41586-022-05439-w. Epub 2022 Nov 16. Nature. 2022. PMID: 36385529 Free PMC article.
Single-cell transcriptomic analysis of Alzheimer's disease.
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH. Mathys H, et al. Nature. 2019 Jun;570(7761):332-337. doi: 10.1038/s41586-019-1195-2. Epub 2019 May 1. Nature. 2019. PMID: 31042697 Free PMC article.
Author Correction: Single-cell transcriptomic analysis of Alzheimer's disease.
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH. Mathys H, et al. Nature. 2019 Jul;571(7763):E1. doi: 10.1038/s41586-019-1329-6. Nature. 2019. PMID: 31209304 Free PMC article.
Inferring multimodal latent topics from electronic health records.
Li Y, Nair P, Lu XH, Wen Z, Wang Y, Dehaghi AAK, Miao Y, Liu W, Ordog T, Biernacka JM, Ryu E, Olson JE, Frye MA, Liu A, Guo L, Marelli A, Ahuja Y, Davila-Velderrain J, Kellis M. Li Y, et al. Nat Commun. 2020 May 21;11(1):2536. doi: 10.1038/s41467-020-16378-3. Nat Commun. 2020. PMID: 32439869 Free PMC article.
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Lee H, Fenster RJ, Pineda SS, Gibbs WS, Mohammadi S, Davila-Velderrain J, Garcia FJ, Therrien M, Novis HS, Gao F, Wilkinson H, Vogt T, Kellis M, LaVoie MJ, Heiman M. Lee H, et al. Neuron. 2020 Sep 9;107(5):891-908.e8. doi: 10.1016/j.neuron.2020.06.021. Epub 2020 Jul 17. Neuron. 2020. PMID: 32681824 Free PMC article.
Perspectives on ENCODE.
ENCODE Project Consortium; Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM. ENCODE Project Consortium, et al. Nature. 2020 Jul;583(7818):693-698. doi: 10.1038/s41586-020-2449-8. Epub 2020 Jul 29. Nature. 2020. PMID: 32728248 Free PMC article.
42 results