Davies A - Search Results

1

Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.

Carr DF, Ayehunie S, Davies A, Duckworth CA, French S, Hall N, Hussain S, Mellor HR, Norris A, Park BK, Penrose A, Pritchard DM, Probert CS, Ramaiah S, Sadler C, Schmitt M, Shaw A, Sidaway JE, Vries RG, Wagoner M, Pirmohamed M. Carr DF, et al. Among authors: davies a. Pharmacol Ther. 2017 Apr;172:181-194. doi: 10.1016/j.pharmthera.2017.01.002. Epub 2017 Jan 27. Pharmacol Ther. 2017. PMID: 28132905 Review.

2

Dual glutathione-S-transferase-θ1 and -μ1 gene deletions determine imatinib failure in chronic myeloid leukemia.

Davies A, Giannoudis A, Zhang JE, Austin G, Wang L, Holyoake TL, Müller MC, Foroni L, Kottaridis PD, Pirmohamed M, Clark RE. Davies A, et al. Clin Pharmacol Ther. 2014 Dec;96(6):694-703. doi: 10.1038/clpt.2014.176. Epub 2014 Sep 4. Clin Pharmacol Ther. 2014. PMID: 25188725

3

Lamotrigine is a substrate for OCT1 in brain endothelial cells.

Dickens D, Owen A, Alfirevic A, Giannoudis A, Davies A, Weksler B, Romero IA, Couraud PO, Pirmohamed M. Dickens D, et al. Among authors: davies a. Biochem Pharmacol. 2012 Mar 15;83(6):805-14. doi: 10.1016/j.bcp.2011.12.032. Epub 2011 Dec 29. Biochem Pharmacol. 2012. PMID: 22227272

4

Serotonin re-uptake transporter gene polymorphisms are associated with imatinib-induced diarrhoea in chronic myeloid leukaemia patients.

Davies A, Rodriguez-Vicente AE, Austin G, Loaiza S, Foroni L, Clark RE, Pirmohamed M. Davies A, et al. Sci Rep. 2020 May 21;10(1):8394. doi: 10.1038/s41598-020-65350-0. Sci Rep. 2020. PMID: 32439979 Free PMC article. Clinical Trial.

5

The clinical significance of ABCC3 as an imatinib transporter in chronic myeloid leukaemia.

Giannoudis A, Davies A, Harris RJ, Lucas CM, Pirmohamed M, Clark RE. Giannoudis A, et al. Among authors: davies a. Leukemia. 2014 Jun;28(6):1360-3. doi: 10.1038/leu.2014.38. Epub 2014 Jan 20. Leukemia. 2014. PMID: 24441286 No abstract available.

6

Pharmacologic markers and predictors of responses to imatinib therapy in patients with chronic myeloid leukemia.

Clark RE, Davies A, Pirmohamed M, Giannoudis A. Clark RE, et al. Among authors: davies a. Leuk Lymphoma. 2008 Apr;49(4):639-42. doi: 10.1080/10428190701858823. Leuk Lymphoma. 2008. PMID: 18398725 Review.

7

Simultaneous determination of nilotinib, imatinib and its main metabolite (CGP-74588) in human plasma by ultra-violet high performance liquid chromatography.

Davies A, Hayes AK, Knight K, Watmough SJ, Pirmohamed M, Clark RE. Davies A, et al. Leuk Res. 2010 Jun;34(6):702-7. doi: 10.1016/j.leukres.2009.11.009. Epub 2009 Dec 9. Leuk Res. 2010. PMID: 20004471

8

Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia.

Giannoudis A, Davies A, Lucas CM, Harris RJ, Pirmohamed M, Clark RE. Giannoudis A, et al. Among authors: davies a. Blood. 2008 Oct 15;112(8):3348-54. doi: 10.1182/blood-2007-10-116236. Epub 2008 Jul 31. Blood. 2008. PMID: 18669873 Free PMC article.

9

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia.

Giannoudis A, Wang L, Jorgensen AL, Xinarianos G, Davies A, Pushpakom S, Liloglou T, Zhang JE, Austin G, Holyoake TL, Foroni L, Kottaridis PD, Müller MC, Pirmohamed M, Clark RE. Giannoudis A, et al. Among authors: davies a. Blood. 2013 Jan 24;121(4):628-37. doi: 10.1182/blood-2012-01-405035. Epub 2012 Dec 5. Blood. 2013. PMID: 23223357 Free article.

10

Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters.

Davies A, Jordanides NE, Giannoudis A, Lucas CM, Hatziieremia S, Harris RJ, Jørgensen HG, Holyoake TL, Pirmohamed M, Clark RE, Mountford JC. Davies A, et al. Leukemia. 2009 Nov;23(11):1999-2006. doi: 10.1038/leu.2009.166. Epub 2009 Aug 27. Leukemia. 2009. PMID: 19710702 Free article.

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